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Table 3 Baseline characteristics and outcomes, treatment with vs. without ICP monitoring

From: Hospital-level intracranial pressure monitoring utilization and functional outcome in severe traumatic brain injury: a post hoc analysis of prospective multicenter observational study

Variables

Overall n = 427

ICP (+) group n = 192

ICP (−) group n = 235

P value

Missing data

Age, years, median [IQR]

65 [46, 77]

65 [45, 76]

66 [50, 79]

0.173

0

Male sex, n (%)

282 (66)

121 (63)

161 (69)

0.259

0

Prescribing anticoagulant drugs, n (%)

19 (4.4)

7 (3.6)

12 (5.1)

0.492

0

Prescribing antiplatelet dugs, n (%)

36 (8.4)

17 (8.9)

19 (8.1)

0.861

0

Glasgow Coma Scale score, median [IQR]

    

0

 Overall score

6 [3, 7]

6 [3, 7]

6 [3, 7]

0.566

 

 Motor score

3 [1, 4]

3 [1, 4]

4 [1, 4.]

0.614

 

Pupillary reflex, n (%)

   

0.002

0

 None

110 (26)

39 (20)

71 (30)

  

 One

91 (21)

55 (29)

36 (15)

  

 Both

226 (53)

98 (51)

128 (55)

  

Hypotension, n (%)

60 (14)

16 (8)

44 (19)

0.002

0

Body temperature, °C, median [IQR]

36.2 [35.8, 36.8]

36.2 [35.8, 36.8]

36.2 [35.8, 36.8]

0.876

34

Marshall CT classification, n (%)

   

0.001

0

 diffuse injury I

9 (2.1)

2 (1.0)

7 (3.0)

  

 diffuse injury II

96 (22.5)

29 (15.1)

67 (28.5)

  

 diffuse injury III

48 (11.2)

24 (12.5)

24 (10.2)

  

 diffuse injury IV

11 (2.6)

5 (2.6)

6 (2.6)

  

 evacuated mass

175 (41.0)

98 (51.0)

77 (32.8)

  

 non-evacuated mass

88 (20.6)

34 (17.7)

54 (23.0)

  

Injury Severity Score, median [IQR]

25 [25, 35]

26 [25, 34]

25 [22, 37]

0.441

0

Isolated traumatic brain injury, n (%)

173 (41)

77 (40)

96 (41)

0.921

0

Cause of injury, n (%)

   

0.703

2

 Motor vehicle

27 (6.3)

12 (6.3)

15 (6.4)

  

 Motorcycle

53 (12.4)

25 (13.1)

28 (12.0)

  

 Bicycle

34 (8.0)

42 (22.0)

48 (20.5)

  

 Pedestrian

90 (21.1)

17 (8.9)

17 (7.3)

  

 High-level fall

115 (27.0)

54 (28.3)

61 (26.1)

  

 Ground-level fall

79 (18.5)

28 (14.7)

51 (21.8)

  

 Others

18 (4.2)

13 (6.8)

14 (6.0)

  

Treatment at university hospitals, n (%)

257 (60)

146 (76.0)

111 (47.2)

< 0.001

0

GOS at 6 months after injury, n (%)

   

0.001

0

 Good recovery

75 (17.6)

28 (14.6)

47 (20.0)

  

 Moderate disability

62 (14.5)

36 8 (18.8)

26 (11.1)

  

 Severe disability

40 (9.4)

21 (10.9)

19 (8.1)

  

 Vegetable state

41 (9.6)

27 (14.1)

14 (6.0)

  

 Death

209 (48.9)

80 (41.7)

129 (54.9)

  

Favorable outcome at 6 months after injury, n (%)

137 (32)

64 (33)

73 (31)

0.677

0

  1. IQR interquartile range, CT computed tomography, ICP intracranial pressure, GOS Glasgow Outcome Scale