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Table 3 Baseline characteristics and treatment parameters of patients in whom eCPR was initiated stratified by survivor status

From: Establishment of an extracorporeal cardio-pulmonary resuscitation program in Berlin – outcomes of 254 patients with refractory circulatory arrest

Baseline characteristics

Variable

All n = 126

Non-survivors n = 108

Survivors n = 18

p-value

Gender (male)

93 (74%)

79 (73%)

14 (78%)

n.s.

Age (years)

52 (42–61)

52 (41–59)

59 (46–66)

n.s.

OHCA

85 (67,5%)

77 (71%)

8 (44%)

< 0,05

EMS first rhythm (shockable)

64 (51%)

53 (49%)

11 (61%)

n.s.

Rhythm on admission (shockable)

32 (25%)

24 (22%)

8 (44%)

< 0,05

Epinephrine (mg; total amount)

7 (4–10)

7 (4–11)

5 (1–7)

< 0,05

Suspected cause of arrest

 Cardiac

76 (60%)

64 (59%)

12 (67%)

n.s.

 Non-cardiac

50 (40%)

44 (41%)

6 (33%)

 APACHE (admission)

41 (38–46)

42 (38–47)

39 (37–43)

n.s.

 Ventilator time (hours)

25 (6–86)

15 (6–59)

722 (242–1003)

< 0.05

eCPR related time intervals

 Collapse to admission (min)

57 (45–67)

60 (46–70)

33 (13–53)

< 0,05

 Collapse to eCPR (min)

89 (73–111)

90 (74–114)

58 (12–85)

< 0,05

 ECPR duration (hours)

20.7 (5.1–63)

12 (5–44.1)

89 (49–153.7)

< 0.05

Admission laboratory values

 pH

7.1 (6.9–7,2)

7 (6.9–7.2)

7.2 (7.15–7.4)

<  0.05

 Lactate

137 (104–173)

143 (111–178)

95 (44–130)

< 0,05

 Potassium

4.3 (3.7–5.1)

4.4 (3.8–5.2)

4 (3.5–4.5)

< 0,05

 INR

1.8 (1.5–3.2)

2 (1.5–3.7)

1.5 (1.3–2.4)

< 0,05

Blood and volume treatment during the 1st 24 h

 Red cell units

4 (2–10)

5.5 (2–12)

2.5 (0–4.5)

< 0,05

 FFP (units)

5 (0–12)

6 (0–12)

4 (0–10.3)

n.s.

 Volume first 24 h (liter)

5 (2.1–8)

5.3 (2.3–8.2)

2.9 (2.1–5.9)

n.s.

Diagnostic procedures

 Coronary angiography

82 (65%)

69 (64%)

13 (72%)

n.s.

 Relevant coronary stenosis

67 (53%)

56 (52%)

11 (61%)

n.s.

 CT (full body scan)

63 (50%)

49 (45%)

14 (78%)

< 0,05

  Normal result

23 (18%)

13 (12%)

10 (56%)

 

  ICH

5 (4%)

4 (4%)

1 (6%)

 

  Brain edema

21 (17%)

20 (19%)

1 (6%)

 

  Pulmonary embolism

7 (6%)

6 (6%)

1 (6%)

 

  Aortic dissection

3 (2%)

3 (3%)

0

 
  1. Data are given as median (25–75% interquartile range) or absolute numbers
  2. OHCA out-of-hospital cardiac arrest, EMS emergency medical service, CA cardiac arrest, APACHE Acute Physiology And Chronic Health Evaluation, eCPR extracorporeal cardiopulmonary resuscitation, INR international normalized ratio, EK erythrocyte concentrate, FFP fresh frozen plasma, CT computer tomography, ICH intracranial hemorrhage