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Table 3 Performance of clinical risk scores at emergency department admission to predict severe disease from covid-19, n = 66

From: National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 – a prospective cohort study

 

Sensitivity %

(95% CI)

Specificity %

(95% CI)

PPV %

(95% CI)

NPV %

(95% CI)

AUC

(95% CI)

NEWS2 ≥ 5

86.7 (59.5–98.3)

70.6 (56.2–82.5)

46.4 (35.2–58.1)

94.7 (83.0–98.5)

0.786 (0.659–0.913)

NEWS2 ≥ 6

80.0 (52.9–95.7)

84.3 (71.4–92.9)

60.0 (43.1–74.8)

93.5 (83.8–97.5)

0.822 (0.690–0.953)

qSOFA ≥ 2

26.7 (7.8–55.1)

98.0 (89.6–100.0)

80.0 (32.6–97.1)

82.0 (77.0–86.1)

0.624 (0.446–0.810)

≥2 SIRS criteria

60.0 (32.3–83.7)

66.7 (52.1–79.2)

34.6 (23.1–48.3)

85.0 (74.8–91.6)

0.633 (0.470–0.796)

CRB-65 ≥ 2

26.7 (7.8–55.1)

90.2 (78.6–96.7)

44.4 (19.7–72.3)

80.7 (75.3–85.2)

0.584 (0.410–0.759)

  1. CI, Confidence interval; PPV, Positive Predictive Value; NPV, Negative Predictive Value; AUC, Area under the Curve; NEWS, National Early Warning Score; qSOFA, Quick Sequential Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome