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Table 3 Performance of clinical risk scores at emergency department admission to predict severe disease from covid-19, n = 66

From: National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 – a prospective cohort study

  Sensitivity %
(95% CI)
Specificity %
(95% CI)
PPV %
(95% CI)
NPV %
(95% CI)
AUC
(95% CI)
NEWS2 ≥ 5 86.7 (59.5–98.3) 70.6 (56.2–82.5) 46.4 (35.2–58.1) 94.7 (83.0–98.5) 0.786 (0.659–0.913)
NEWS2 ≥ 6 80.0 (52.9–95.7) 84.3 (71.4–92.9) 60.0 (43.1–74.8) 93.5 (83.8–97.5) 0.822 (0.690–0.953)
qSOFA ≥ 2 26.7 (7.8–55.1) 98.0 (89.6–100.0) 80.0 (32.6–97.1) 82.0 (77.0–86.1) 0.624 (0.446–0.810)
≥2 SIRS criteria 60.0 (32.3–83.7) 66.7 (52.1–79.2) 34.6 (23.1–48.3) 85.0 (74.8–91.6) 0.633 (0.470–0.796)
CRB-65 ≥ 2 26.7 (7.8–55.1) 90.2 (78.6–96.7) 44.4 (19.7–72.3) 80.7 (75.3–85.2) 0.584 (0.410–0.759)
  1. CI, Confidence interval; PPV, Positive Predictive Value; NPV, Negative Predictive Value; AUC, Area under the Curve; NEWS, National Early Warning Score; qSOFA, Quick Sequential Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome