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Table 1 Characteristics and symptoms at admission in hospitalised patients with covid-19 admitted in the period from March 9th to April 27th 2020 by disease severity, n = 66

From: National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 – a prospective cohort study

  Severe disease
(n = 15)
Less severe disease (n = 51) p-value
Mean (SD) Mean (SD)  
Age (years) 75.8 (13.6) 65.6 (16.4) < 0.05
Clinical Frailty Scale score1 3.7 (2.4) 3.0 (2.0) 0.31
Charlson Comorbidity Index 5.3 (3.9) 2.9 (2.5) < 0.05
Body mass index (kilograms/m2)2 23.4 (4.2) 26.3 (4.2) 0.09
Days of symptoms prior to admission 6.9 (3.8) 8.7 (5.0) 0.15
  n (%) n (%)  
Male gender 12 (80) 26 (51) < 0.05
Admitted from nursing home 2 (13) 2 (4) 0.31
Current or previous smoking3 4 (27) 14 (33) 0.67
Clinical Frailty Scale score    0.10
 1–2 (fit) 7 (47) 24 (47)  
 3–4 (managing well or vulnerable) 1 (7) 15 (29)  
  ≥ 5 (moderately or severely frail) 7 (47) 12 (24)  
Charlson Comorbidity Index    0.10
 0–2 3 (20) 25 (49)  
 3–5 7 (47) 18 (35)  
  > 5 5 (33) 8 (16)  
Co-morbidities
 Hypertension 4 (27) 15 (29) 0.84
 Diabetes mellitus 3 (20) 5 (10) 0.36
 Cardiac conditions 3 (20) 8 (16) 0.69
 Chronic kidney disease 2 (13) 5 (10) 0.70
 Malignancy 3 (20) 6 (12) 0.41
 Asthma 0 (0) 7 (14) 0.13
 COPD4 4 (27) 1 (2) < 0.05
 Others 2 (13) 9 (18) 0.69
Symptoms
 Cough 8 (53) 32 (63) 0.51
 Dyspnoea 13 (87) 30 (59) < 0.05
 Fever 10 (67) 36 (71) 0.77
 Reduced general condition 14 (93) 39 (76) 0.15
 New confusion 5 (33) 6 (12) < 0.05
 Gastrointestinal 5 (33) 9 (18) 0.19
 Others 1 (7) 21 (41) < 0.05
  1. 1 Based on functional status 14 days prior to acute illness. 2 Missing data for 17 patients (6 with severe illness and 11 with less severe illness). 3 Missing data for 8 patients with less severe illness. 4 Chronic obstructive pulmonary disease