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Table 1 Characteristics and symptoms at admission in hospitalised patients with covid-19 admitted in the period from March 9th to April 27th 2020 by disease severity, n = 66

From: National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 – a prospective cohort study

 

Severe disease

(n = 15)

Less severe disease (n = 51)

p-value

Mean (SD)

Mean (SD)

 

Age (years)

75.8 (13.6)

65.6 (16.4)

< 0.05

Clinical Frailty Scale score1

3.7 (2.4)

3.0 (2.0)

0.31

Charlson Comorbidity Index

5.3 (3.9)

2.9 (2.5)

< 0.05

Body mass index (kilograms/m2)2

23.4 (4.2)

26.3 (4.2)

0.09

Days of symptoms prior to admission

6.9 (3.8)

8.7 (5.0)

0.15

 

n (%)

n (%)

 

Male gender

12 (80)

26 (51)

< 0.05

Admitted from nursing home

2 (13)

2 (4)

0.31

Current or previous smoking3

4 (27)

14 (33)

0.67

Clinical Frailty Scale score

  

0.10

 1–2 (fit)

7 (47)

24 (47)

 

 3–4 (managing well or vulnerable)

1 (7)

15 (29)

 

  ≥ 5 (moderately or severely frail)

7 (47)

12 (24)

 

Charlson Comorbidity Index

  

0.10

 0–2

3 (20)

25 (49)

 

 3–5

7 (47)

18 (35)

 

  > 5

5 (33)

8 (16)

 

Co-morbidities

 Hypertension

4 (27)

15 (29)

0.84

 Diabetes mellitus

3 (20)

5 (10)

0.36

 Cardiac conditions

3 (20)

8 (16)

0.69

 Chronic kidney disease

2 (13)

5 (10)

0.70

 Malignancy

3 (20)

6 (12)

0.41

 Asthma

0 (0)

7 (14)

0.13

 COPD4

4 (27)

1 (2)

< 0.05

 Others

2 (13)

9 (18)

0.69

Symptoms

 Cough

8 (53)

32 (63)

0.51

 Dyspnoea

13 (87)

30 (59)

< 0.05

 Fever

10 (67)

36 (71)

0.77

 Reduced general condition

14 (93)

39 (76)

0.15

 New confusion

5 (33)

6 (12)

< 0.05

 Gastrointestinal

5 (33)

9 (18)

0.19

 Others

1 (7)

21 (41)

< 0.05

  1. 1 Based on functional status 14 days prior to acute illness. 2 Missing data for 17 patients (6 with severe illness and 11 with less severe illness). 3 Missing data for 8 patients with less severe illness. 4 Chronic obstructive pulmonary disease