The association of partial pressures of oxygen and carbon dioxide with neurological outcome after out-of-hospital cardiac arrest: an explorative International Cardiac Arrest Registry 2.0 study

Table 2 Association of exposure to extreme PaO₂ and PaCO₂ values with poor neurological outcome

Analysis	OR	95% CI	P-Value
Hyperoxemia versus PaO₂ no-exposure	1.33	0.92–1.92	0.13
Hyperoxemia versus no-hyperoxemia	1.25	0.88–1.77	0.22
Hypoxemia versus PaO₂ no-exposure	1.26	0.87–1.82	0.22
Hypoxemia versus no-hypoxemia	1.15	0.81–1.64	0.44
Hypercapnemia versus PaCO₂ no-exposure	0.89	0.64–1.24	0.49
Hypercapnemia versus no-hypercapnemia	0.86	0.64–1.15	0.31
Hypocapnemia versus PaCO₂ no-exposure	1.28	0.90–1.83	0.18
Hypocapnemia versus no-hypocapnemia	1.23	0.91–1.66	0.18

OR odds ratio, 95% CI 95% confidence interval, PaO₂ arterial partial pressure of oxygen, PaCO₂ arterial partial pressure of carbon dioxide. Hyperoxemia = PaO₂ > 40 kPa, Hypoxemia = PaO₂ < 8.0 kPa, Hypercapnemia = PaCO₂ > 6.7 kPa, Hypocapnemia = PaCO₂ < 4.0 kPa. PaO₂ no-exposure = 8.0–40 kPa PaCO₂ no-exposure = 4.0–6.7 kPa

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