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Table 1 Patients’ characteristics for the period before (Period 1, 2005–2007) and after (Period 2, 2012–2014) the implementation of a goal-directed factor-based coagulation algorithm. Values are means with standard deviations or counts and proportions

From: Impact of a goal-directed factor-based coagulation management on thromboembolic events following major trauma

 

Period 1 (2005–2007)

n = 344

Period 2 (2012–2014)

n = 428

Age - years

42.0 (19.0)

51.5 (21.8)

Sex - male

268 (78%)

315 (74%)

Penetrating trauma

29 (8.4%)

16 (3.7%)

Injury severity score

33 (13)

34 (19)

AIS head

3 (2)

3 (2)

AIS thorax

2 (2)

2 (2)

AIS abdomen

1 (2)

1 (1)

AIS extremities

1 (1)

1 (2)

Laboratory values

 Haemoglobin - g/L

111 (29)

107 (53)

 Platelet count on entry - 103/mcL

211 (68)

198 (81)

 Base Excess on entry - mmol/L

−4.7 (4.6)

−4.4 (5.0)

 Lactate on entry - mmol/L

3.2 (2.4)

2.6 (2.4)

 Fibrinogen on entry - g/L

1.9 (0.8)

2.2 (0.9)

 INR on hospital admission

1.26 (0.5)

1.34 (0.5)

Coagulation factors and allogeneic blood products

 In-hospital TXA

3 (0.9%)

209 (50%)

 Fibrinogen

130 (38%)

138 (32%)

 PCC

15 (4.4%)

39 (9.1%)

 Factor XIII

0

53 (12%)

Transfusion of any allogeneic blood product

181 (53%)

140 (33%)

 RBC

175 (51%)

113 (26%)

 PC

56 (16%)

66 (15%)

 FFP

122 (36%)

67 (16%)

  1. AIS Abbreviated Injury Scale, RBC Red Blood Cell, PC Platelet Concentrate, FFP Fresh Frozen Plasma, PCC Prothrombin Complex Concentrate, TXA Tranexamic Acid