Table 1 Characteristics and type of pain for male patients in the derivation set with and without a diagnosis of acute coronary syndrome (ACS)
Total (n = 1398) | ACS (n = 329) | No ACS (n = 1069) | p value | |
|---|---|---|---|---|
Age, mean (SD), y, No. (%) | 59.2 (16.1) | 59.4 (13.2) | 50.9 (16.4) | < 0.001 |
< 40 | 291 (20.8) | 18 (5.5) | 273 (25.5) | < 0.001 |
40–50 | 317 (22.7) | 59 (17.9) | 258 (24.1) | |
50–60 | 320 (22.9) | 95 (28.9) | 225 (21.0) | |
≥ 60 | 470 (33.6) | 157 (47.7) | 313 (29.3) | |
Coexisting conditions, No. (%) | ||||
Hypertension | 405 (29.0) | 123 (37.4) | 282 (26.4) | < 0.001 |
Personal coronary artery disease | 387 (27.7) | 126 (38.3) | 261 (24.4) | < 0.001 |
Family coronary artery disease | 231 (16.5) | 51 (15.5) | 180 (16.8) | 0.568 |
Tobacco use | 545 (39.0) | 133 (40.4) | 412 (38.5) | 0.540 |
Diabetes | 183 (13.1) | 59 (17.9) | 124 (11.6) | 0.003 |
Dyslipidaemia | 337 (24.1) | 97 (29.5) | 240 (22.5) | 0.009 |
Medication therapy, No. (%) | ||||
Aspirin | 296 (21.2) | 100 (30.4) | 196 (18.3) | < 0.001 |
Clopidogrel | 209 (14.9) | 77 (23.4) | 132 (12.3) | < 0.001 |
Thyroid hormone | 12 (0.9) | 2 (0.6) | 10 (0.9) | 0.743 |
Statin | 263 (18.8) | 87 (26.4) | 176 (16.5) | < 0.001 |
Severity of pain, median (IQR) | 5 [3–7] | 5 [4–7] | 5 [3–7] | < 0.001 |
Type of pain, No. (%) | ||||
Severe pain (NRS ≥6) | 592 (42.4) | 162 (49.2) | 430 (40.3) | 0.004 |
Permanent | 350 (25.0) | 102 (31.0) | 248 (23.2) | 0.004 |
Pain onset: | 0.066 | |||
Crescendo | 307 (22.0) | 67 (20.4) | 240 (22.5) | |
Abruptly | 590 (42.2) | 157 (47.7) | 433 (40.5) | |
Unclassified | 501 (35.8) | 105 (31.9) | 396 (37.0) | |
Circumstance of pain, No. (%) | 0.012 | |||
At rest | 1106 (79.1) | 244 (74.2) | 862 (80.6) | |
Sport or stress-related | 180 (12.9) | 58 (17.6) | 122 (11.4) | |
Unclassified | 112 (8.0) | 27 (8.2) | 85 (8.0) | |
Pain typography, No. (%) | ||||
Typical chest paina | 799 (57.2) | 224 (68.1) | 575 (53.8) | < 0.001 |
Retrosternal | 671 (48.0) | 201 (61.1) | 470 (44.0) | < 0.001 |
Post-myocardial infarction angina | 119/387 (30.8) | 50/126 (39.7) | 69/261 (24.4) | 0.008 |
Peak type | 260 (18.6) | 28 (8.5) | 232 (21.7) | < 0.001 |
Burning | 182 (13.0) | 51 (15.5) | 131 (12.3) | 0.126 |
Pinching | 81 (5.8) | 7 (2.1) | 74 (6.9) | 0.001 |
Increasing at position change | 252 (18.0) | 29 (8.8) | 223 (20.9) | < 0.001 |
Breathing non-related | 1037 (74.2) | 299 (90.9) | 738 (69.0) | < 0.001 |
Radiating | 592 (42.3) | 179 (54.4) | 413 (38.6) | < 0.001 |
Additional symptoms | 937 (67.1) | 249 (75.7) | 688 (64.4) | < 0.001 |