Skip to main content

Table 2 bacterial forms of sepsis-causing bacteria, types of sepsis and the optimal strategies of antibacterial treatment

From: Sepsis: mechanisms of bacterial injury to the patient

Bacterial form

Types of sepsis

Sensitivity to antibacterials

Respiration, Metabolism

Defense against host

Treatment strategies

Planktonic

Sepsis

Severe sepsis

Septic shock

Fulminant sepsis

High

High

Toxins

Catalase

SOD, GPX,

Hemolysins…

Appropriate antibacterials

Toxin production inhibition

Toxin binding and removal

Antioxidant enzyme inhibition

Inhibition of hemolysins

Removal by mechanical device

Encapsulated

Subacute sepsis

Chronic sepsis

Relapsing sepsis

Indolent sepsis

Latent sepsis

Dormant sepsis

Moderate

Moderate

Capsular

polysaccharides

Appropriate antibacterials

Capsule production inhibition

Biofilm

Low

Low

Biofilm polymers

Appropriate antibacterials after using antibiofilm drugs

L-form

Very low

Very low

Entering host cells

Not available

  1. Abbreviations: SOD Superoxide dismutase, GPX Glutathione peroxidase