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Table 2 bacterial forms of sepsis-causing bacteria, types of sepsis and the optimal strategies of antibacterial treatment

From: Sepsis: mechanisms of bacterial injury to the patient

Bacterial form Types of sepsis Sensitivity to antibacterials Respiration, Metabolism Defense against host Treatment strategies
Planktonic Sepsis Severe sepsis Septic shock Fulminant sepsis High High Toxins Catalase SOD, GPX, Hemolysins… Appropriate antibacterials Toxin production inhibition Toxin binding and removal Antioxidant enzyme inhibition Inhibition of hemolysins Removal by mechanical device
Encapsulated Subacute sepsis Chronic sepsis Relapsing sepsis Indolent sepsis Latent sepsis Dormant sepsis Moderate Moderate Capsular polysaccharides Appropriate antibacterials Capsule production inhibition
Biofilm Low Low Biofilm polymers Appropriate antibacterials after using antibiofilm drugs
L-form Very low Very low Entering host cells Not available
  1. Abbreviations: SOD Superoxide dismutase, GPX Glutathione peroxidase