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Table 2 bacterial forms of sepsis-causing bacteria, types of sepsis and the optimal strategies of antibacterial treatment

From: Sepsis: mechanisms of bacterial injury to the patient

Bacterial form Types of sepsis Sensitivity to antibacterials Respiration, Metabolism Defense against host Treatment strategies
Planktonic Sepsis
Severe sepsis
Septic shock
Fulminant sepsis
High High Toxins
Catalase
SOD, GPX,
Hemolysins…
Appropriate antibacterials
Toxin production inhibition
Toxin binding and removal
Antioxidant enzyme inhibition
Inhibition of hemolysins
Removal by mechanical device
Encapsulated Subacute sepsis
Chronic sepsis
Relapsing sepsis
Indolent sepsis
Latent sepsis
Dormant sepsis
Moderate Moderate Capsular
polysaccharides
Appropriate antibacterials
Capsule production inhibition
Biofilm Low Low Biofilm polymers Appropriate antibacterials after using antibiofilm drugs
L-form Very low Very low Entering host cells Not available
  1. Abbreviations: SOD Superoxide dismutase, GPX Glutathione peroxidase