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Table 2 Table of results for all variables measured pre- and post-venesection

From: Investigating the ability of non-invasive measures of cardiac output to detect a reduction in blood volume resulting from venesection in spontaneously breathing subjects

Measurement (units)

n

# increased following venesection

# decreased following venesection

# no change following venesection

pre-venesection mean

post-venesection mean

Average Change (95% CI)

Inverse Coefficient of Variation (1/CV) (95% CI)

Log-odds (95% CI)

Heart Rate (bpm)

40

7

31

2

77.30

71.47

−5.83 (−7.72, −3.88)

− 0.92 (− 1.37, − 0.59)

− 1.39 (− 2.35, − 0.73)

Diastolic blood pressure (mmHg)

40

11

27

2

74.83

71.30

−3.52 (− 5.85, −1.15)

− 0.46 (− 0.90, − 0.14)

− 0.85 (− 1.64, − 0.25)

Systolic blood pressure (mmHg)

40

6

32

2

136.25

125.38

− 10.88 (− 14.57, − 7.35)

− 0.93 (− 1.28, − 0.67)

− 1.55 (− 2.51, − 0.85)

Mean Arterial Pressure (mmHg)

40

5

34

1

97.78

91.33

−6.45 (−8.57, −4.22)

− 0.91 (− 1.50, − 0.52)

− 1.84 (− 2.94, − 1.10)

IVCe (cm)

29

4

25

0

1.76

1.49

− 0.26 (− 0.37, − 0.16)

− 0.87 (− 1.26, − 0.57)

−1.83 (− 3.33, − 0.97)

IVCi (cm)

29

2

22

5

0.94

0.69

− 0.25 (− 0.37, − 0.14)

−0.80 (− 1.18, − 0.57)

−1.70 (− 2.91, − 0.97)

IVCCI %

29

16

9

4

48

59

10 (3.9, 19)

0.51 (0.30, 0.73)

0.49 (−0.21, 1.24)

Tcol (seconds)

22

2

20

0

2.02

1.267

−0.75 (−1.15, − 0.39)

−0.78 (− 1.23, − 0.47)

−2.30 (-Inf, − 1.22)

Carotid artery blood flow (ml/min)

39

21

18

0

720.1

731.8

11.4 (−29.6, 52.1)

0.09 (−0.22, 0.44)

0.15 (−0.47, 0.81)

r-r interval (seconds)

40

12

18

10

0.90

0.89

−0.0092 (− 0.027, 0.0090)

−0.16 (− 0.49, 0.15)

−0.30 (− 0.85, 0.25)

Flow time (seconds)

40

12

19

9

0.31

0.31

−0.0048 (− 0.011, 0.0018)

−0.22 (− 0.54, 0.09)

−0.35 (− 0.97, 0.20)

Corrected flow time (seconds)

40

18

21

1

0.33

0.33

−0.0040 (− 0.012, 0.0037)

−0.16 (− 0.48, 0.15)

−0.15 (− 0.79, 0.46)

ECHO VTI (cm)

38

8

30

0

21.87

20.34

−1.47 (−2.11, −0.85)

−0.73 (− 1.09, − 0.45)

−1.32 (− 2.46, − 0.65)

ECHO CO (L/min)

38

3

35

0

6.28

5.39

− 0.86 (−1.12, − 0.61)

− 1.03 (− 1.53, − 0.74)

−2.46 (-Inf, − 1.49)

ECHO SV (ml)

38

8

30

0

80.00

74.02

−5.24 (− 7.65, −2.88)

−0.70 (− 1.06, − 0.40)

− 1.32 (− 2.46, − 0.65)

USCOM 1A CO (L/min)

37

14

22

1

4.35

4.13

− 0.18 (− 0.45, 0.10)

−0.21 (− 0.62, 0.11)

−0.44 (− 1.14, 0.22)

USCOM 1A SV (ml)

37

11

25

1

64.87

60.66

−3.19 (− 6.57, 0.57)

−0.28 (− 0.74, 0.05)

−0.80 (− 1.55, − 0.16)

LiDCOrapidv2 with CNAP™ CO (L/min)

37

16

21

0

7.29

6.49

−0.80 (− 1.41, − 0.22)

−0.42 (− 0.72, − 0.13)

−0.27 (− 0.99, 0.38)

LiDCOrapidv2 with CNAP™ PPV %

36

22

12

2

13.70

16.47

3.00 (0.86, 5.28)

0.43 (0.14, 0.74)

0.57 (−0.06, 1.34)

LiDCOrapidv2 with CNAP™ SV (ml)

37

14

21

2

101.22

90.62

−10.59 (− 19.54, − 2.16)

−0.39 (− 0.70, − 0.09)

−0.38 (− 1.06, 0.22)

LiDCOrapidv2 with CNAP™ SVV %

36

18

13

5

15.95

17.89

2.08 (−0.17, 4.56)

0.28 (−0.03, 0.57)

0.28 (− 0.34, 0.96)

  1. n is the number of paired scans included in final analysis. #increase and #decrease show the number of measurement that increased and decreased in magnitude following venesection respectively. IVCe maximum inferior vena cava diameter on expiration, IVCi minimum inferior vena cave diameter on inspiration, IVCCI inferior vena cava collapsibility index, Tcol time taken for complete IVC collapse during controlled inspiratory manoeuvre, ECHO transthoracic echocardiography, VTI velocity time integral, CO cardiac output, SV stroke volume, USCOM Ultrasound Cardiac Output Monitor, SVV stroke volume variation, PPV Pulse pressure variation