Table 3 Standard mechanical CPR compared with ACD CPR during different CPR cycle phases
Standard CPR mean ± SD | ACD-CPR mean ± SD | Mean difference (95% CI) | Standard CPR median (quartiles) | ACD-CPR median (quartiles) | p-value | |
|---|---|---|---|---|---|---|
Blood pressures (mmHg) | ||||||
Aortic pressure | ||||||
Peak compression | 180 ± 78 | 196 ± 79 | 16 (1.1, 30) | 0.04 | ||
End compression | 73 ± 65 | 68 ± 85 | −4.9 (−29, 19) | 0.65 | ||
Low decompression | 10 ± 11 | 8.7 ± 13 | −1.4 (−8.6, 5.8) | 0.66 | ||
End decompression | 28 ± 10 | 30 ± 9.1 | 2.0 (− 1.1, 5.2) | 0.18 | ||
Right atrial pressure | ||||||
Peak compression | 172 ± 71 | 180 ± 75 | 7.8 (− 17, 33) | 0.49 | ||
End compression | 91 ± 31 | 97 ± 32 | 6.3 (−3.2, 16) | 0.16 | ||
Low decompression | 7.7 (5.5, 22) | 13 (5.6, 21) | 0.59 | |||
End decompression | 11 (11, 18) | 11 (9.4, 17) | 0.11 | |||
Coronary perfusion pressure | ||||||
Peak compression | 8.3 ± 39 | 16 ± 44 | 7.8 (−9.8, 25) | 0.34 | ||
End compression | −21 (−39, 6.0) | −19 (− 39, 6.5) | 0.59 | |||
Low decompression | −1.2 ± 14 | −6.2 ± 17 | −4.9 (− 11, 1.4) | 0.11 | ||
End decompression | 12 ± 11 | 16 ± 9.4 | 4.3 (−0.2, 8.7) | 0.06 | ||
Intracranial pressure | ||||||
Peak compression | 38 (28, 44) | 41 (24, 45) | 0.37 | |||
End compression | 35 ± 10 | 35 ± 12 | −0.2 (−4.2, 3.8) | 0.91 | ||
Low decompression | 23 ± 8.3 | 24 ± 6.7 | 1.4 (−2.1, 4.8) | 0.39 | ||
End decompression | 15 ± 4.9 | 14 ± 5.2 | −0.7 (−1.2, − 0.1) | 0.03 | ||
Oesophageal pressure | ||||||
Peak compression | 106 ± 83 | 118 ± 94 | 13 (−17, 42) | 0.35 | ||
End compression | 76 ± 48 | 84 ± 51 | 7.4 (−3.3, 18) | 0.15 | ||
Low decompression | 40 ± 37 | 40 ± 34. | −0.4 (−12, 11) | 0.94 | ||
End decompression | 39 ± 29 | 39 ± 32 | 0.0 (−7.8, 7.7) | 0.99 | ||
Blood flow | ||||||
Cerebral flow (AU) | ||||||
Peak compression | 248 ± 268 | 285 ± 261 | 38 (9.8, 66) | 0.01 | ||
End compression | 244 ± 255 | 278 ± 251 | 34 (8.7, 60) | 0.02 | ||
Low decompression | 250 ± 257 | 288 ± 254 | 38 (5.3, 70) | 0.03 | ||
End decompression | 266 ± 283 | 316 ± 283 | 51 (18, 82) | < 0.01 | ||
Carotid artery flow (ml/min) | ||||||
Peak compression | 288 ± 93 | 311 ± 106 | 23 (−16, 62) | 0.21 | ||
End compression | 159 (59, 321) | 176 (100, 223) | 0.17 | |||
Low decompression | 7.7 (−99, 51) | 17 (−47, 97) | 0.37 | |||
End decompression | 22 (−19, 98) | 38 (−7.7, 117) | 0.09 | |||