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Table 3 Standard mechanical CPR compared with ACD CPR during different CPR cycle phases

From: Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest

  Standard CPR mean ± SD ACD-CPR mean ± SD Mean difference (95% CI) Standard CPR median (quartiles) ACD-CPR median (quartiles) p-value
Blood pressures (mmHg)
 Aortic pressure
  Peak compression 180 ± 78 196 ± 79 16 (1.1, 30)   0.04
  End compression 73 ± 65 68 ± 85 −4.9 (−29, 19)   0.65
  Low decompression 10 ± 11 8.7 ± 13 −1.4 (−8.6, 5.8)   0.66
  End decompression 28 ± 10 30 ± 9.1 2.0 (− 1.1, 5.2)   0.18
 Right atrial pressure
  Peak compression 172 ± 71 180 ± 75 7.8 (− 17, 33)   0.49
  End compression 91 ± 31 97 ± 32 6.3 (−3.2, 16)   0.16
  Low decompression     7.7 (5.5, 22) 13 (5.6, 21) 0.59
  End decompression     11 (11, 18) 11 (9.4, 17) 0.11
 Coronary perfusion pressure
  Peak compression 8.3 ± 39 16 ± 44 7.8 (−9.8, 25)   0.34
  End compression     −21 (−39, 6.0) −19 (− 39, 6.5) 0.59
  Low decompression −1.2 ± 14 −6.2 ± 17 −4.9 (− 11, 1.4)   0.11
  End decompression 12 ± 11 16 ± 9.4 4.3 (−0.2, 8.7)   0.06
 Intracranial pressure
  Peak compression     38 (28, 44) 41 (24, 45) 0.37
  End compression 35 ± 10 35 ± 12 −0.2 (−4.2, 3.8)   0.91
  Low decompression 23 ± 8.3 24 ± 6.7 1.4 (−2.1, 4.8)   0.39
  End decompression 15 ± 4.9 14 ± 5.2 −0.7 (−1.2, − 0.1)   0.03
 Oesophageal pressure
  Peak compression 106 ± 83 118 ± 94 13 (−17, 42)   0.35
  End compression 76 ± 48 84 ± 51 7.4 (−3.3, 18)   0.15
  Low decompression 40 ± 37 40 ± 34. −0.4 (−12, 11)   0.94
  End decompression 39 ± 29 39 ± 32 0.0 (−7.8, 7.7)   0.99
Blood flow
 Cerebral flow (AU)
  Peak compression 248 ± 268 285 ± 261 38 (9.8, 66)   0.01
  End compression 244 ± 255 278 ± 251 34 (8.7, 60)   0.02
  Low decompression 250 ± 257 288 ± 254 38 (5.3, 70)   0.03
  End decompression 266 ± 283 316 ± 283 51 (18, 82)   < 0.01
 Carotid artery flow (ml/min)
  Peak compression 288 ± 93 311 ± 106 23 (−16, 62)   0.21
  End compression   159 (59, 321) 176 (100, 223) 0.17
  Low decompression   7.7 (−99, 51) 17 (−47, 97) 0.37
  End decompression   22 (−19, 98) 38 (−7.7, 117) 0.09