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Table 2 Comparison between standard mechanical CPR and ACD CPR

From: Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest

  Standard CPR mean ± SD ACD-CPR mean ± SD Mean difference (95% CI) Standard CPR median (quartiles) ACD-CPR median (quartiles) p-value
Blood pressures (mmHg)
 Aortic pressure   55 (51, 70) 60 (51, 70) 0.86
 Right atrial pressure 54 ± 16 55 ± 16 1.0 (− 4.0, 6.0)   0.66
 Coronary perfusion pressure 2.2 ± 22 0.6 ± 20 − 2.7 (− 10, 4.7)   0.42
 Oesophageal pressure 57 ± 38 60 ± 39 2.6 (− 2.6, 7.8)   0.28
 Intracranial pressure 24 ± 6.4 23 ± 6.7 −0.7 (− 1.6, 0.1)   0.09
Blood flow
 Cerebral flow (AU) 253 ± 268 297 ± 264 44 (14, 74)   0.01
 Carotid artery flow (ml/min)   83 (57, 94) 97 (70, 106) < 0.01
Manual measurements
 Cardiac output (l/min)   1.1 (0.8, 1.5) 1.5 (1.1, 1.7) < 0.01
 End tidal CO2 (kPa) 2.2 ± 0.8 2.5 ± 1.0 0.3 (− 0.1, 0.7)    0.15
Blood gases (kPa)
 pH - Arterial   7.3 (7.2, 7.4) 7.3 (7.2, 7.4) 0.33
 pCO2 - Arterial   5.6 (4.9, 8.0) 5.4 (4.4, 8.1) 0.89
 pO2 - Arterial 22 ± 20 25 ± 21 2.5 (−6.2, 11)    0.52
 pH - Venous   7.1 (7.1, 7.2) 7.2 (7,1, 7.2) 0.09
 pCO2 - Venous 11 ± 1.9 11 ± 1.9 −0.3 (− 0.5, 0.0)   0.06
 pO2 - Venous   3.1 (3.0, 3.6) 3.3 (3.1, 3.6) 0.11