Skip to main content

Table 3 Laboratory values upon emergency room admission

From: The impact of direct oral anticoagulants in traumatic brain injury patients greater than 60-years-old

 

no ATT

PI

VKA

DOAC

p value

Hb

13.7 (12.4–14.6)

13.5 (11.5–14.9)

13.3 (11.7–14.2)

12.8 (11.8–13.8)

ns

PTI

104 (95–112)

102 (91–115)

30.5 (23.5–36.0)

70 (56.5–83)

< 0.0001

INR

0.98 (0.93–1.04)

1 (0.93–1.06)

2.51 (2.04–3.24)

1.3 (1.1–1.97)

< 0.0001

aPTT

26.9 (25.1–28.8)

27.9 (26.6–30.2)

39.7 (34.6–41.9)

34.1 (28.8–41.0)

< 0.0001

PLT

228 (182–262)

206 (162.5–257.5)

181 (165–212.5)

216 (172–257)

0.0355

S 100β initial

0.66 (0.28–1.53)

0.34 (0.12–0.95)

0.35 (0.13–1.13)

0.25 (0.12–0.97)

ns

Creatinine

0.88 (0.74–1.02)

0.9 (0.67–1.09)

1.02 (0.8–1.29)

1 (0.8–1.2)

ns

GFR

70.6 (51.5–93.4)

64.18 (48.7–87.7)

56.6 (44.1–72.5)

58.7 (44.3–76.1)

ns

AST

25 (20–39)

22 (17.25–29)

27 (19–34)

25 (17–34.5)

ns

Multiplate®

 ASPI* (n = 16, 23, 6, 5)

86.5 (42.5–117.8)

19 (11–39)

61 (20–115)

68 (33–125)

0.0084

 ADP (n = 16, 11, 6, 5)

87.5 (62.25–115.3)

50 (33–84)

72.5 (40–135)

86 (66–116)

ns

 TRAP (n = 16, 10, 6,5)

124 (88.5–146.8)

99.5 (93.3–112.3)

109.5 (94.3–128.5)

127 (108.5–152.5)

ns

  1. No-ATT no antithrombotic therapy, PI platelet inhibitors, VKA vitamin K antagonists DOAC, direct oral anticoagulants, Hb haemoglobin, PTI prothrombin time index, aPTT activated partial thromboplastin time, INR international normalized ratio, PLT platelet count, GFR glomerular filtration rate, AST Aspartate Aminotransferase, ASPI-test arachidonic acid test, ADP-test adenosine diphosphate test, TRAP-test thrombin receptor activated peptide test, ns not significant
  2. ANOVA and Dunnett’s comparison of all columns vs. control column
  3. Median (interquartile range, 25th–75th)