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Table 1 Extended haemodynamic and blood gas parameters

From: Effect of gelatin-polysuccinat on cerebral oxygenation and microcirculation in a porcine haemorrhagic shock model

Parameter
Mean (SD)
  BLH Shock 0 h 1 h 2 h
number of animals GP 9 9 9 9 9
BEL 9 9 9 9 9
Control 9 3 3 3 3
[mmHg] GP 73 (12) 34 (18)* 86 (12)*#2 78 (15)#2 74 (15)
BEL 72 (9) 27 (3)* 84 (10)*#3 68 (10) 65 (8)2
Control 66 (12) 31 (3)* 48 (6)*#2,3 58 (12)#1 61 (11)
HR
[min−1]
GP 70 (16) 101 (37)* 108 (29)*#2 103 (41)*#2 97 (39)*#2
BEL 77 (28) 143 (60)* 102 (34)*#3 109 (46)*#3 120 (51)*
Control 80 (8) 151 (36)* 170 (38)*#2,3 172 (60)*#2,3 172 (68)*#2
CO
[%]
GP 100 60 (20)* 178 (34)*#1,2 155 (19)*#1,2 136 (22)*#1,2
BEL 100 57 (13)* 130 (22)*#1,3 105 (16)#1 105 (14)#1
Control 100 59 (21)* 81 (24)#2,3 84 (31)#2 90 (25)#2
EVLWI
[%]
GP 100 97 (18) 100 (21) 101 (17) 95 (12)
BEL 100 103 (11) 98 (9) 97 (16) 98 (18)
Control 100 108 (34) 90 (10) 81 (9) 84 (14)
GEDI
[%]
GP 100 64 (7)* 114 (10)*#1,2 96 (38)*#2 102 (15)#1,2
BEL 100 67 (11)* 84 (32)#1 83 (16) 84 (13)#1
Control 100 62 (7)* 67 (4)#2 65 (14)#2 68 (16)#2
CVP
[mmHg]
GP 8 (3) 4 (3)* 11 (2)*#1,2 8 (2) 7 (1)
BEL 8 (2) 4 (1)* 8 (2)#1 6 (1)* 6 (2)*
Control 8 (2) 5 (1) 9 (2)#2 5 (2) 5 (3)
SpO2
[%]
GP 100 (1) 97 (4) 98 (2) 99 (2) 99 (1)
BEL 100 (0) 100 (0) 100 (0) 100 (0) 100 (0)
Control 100 (0) 100 (0) 100 (0) 100 (0) 100 (0)
SvO2
[%]
GP 77 (8) 43 (21)*#1,2 75 (11)#1,2 68 (10)#1,2 62 (11)*#2
BEL 72 (14) 31 (14)*#1 60 (10)*#1,3 52 (14)*#1,3 54 (9)*#3
Control 72 (8) 18 (8)*#2 27 (8)*#2,3 34 (4)*#2,3 38 (7)*#2,3
pH GP 7.46 (0,04) 7.39 (0,09) 7.39 (0,04) 7.47 (0,08) 7.45 (0,08)
BEL 7.49 (0,05) 7.45 (0,05) 7.41 (0,06) 7.47 (0,06) 7.49 (0,05)
Control 7.57 (0) 7.54 (0,04) 7.47 (0,06) 7.47 (0,06) 7.49 (0,06)
BE
[mmol/l]
GP 6 (4) 1 (4) 2 (3) 7 (2) 5 (3)
BEL 6 (3) 2 (3) 3 (3) 6 (3) 7 (3)
Control 9 (0) 7 (1) 5 (3) 5 (6) 7 (5)
PaCO2
[mmHg]
GP 42 (5) 44 (10) 45 (8) 44 (8) 46 (10)
BEL 38 (3) 38 (2) 44 (3)* 41 (3) 40 (3)
Control 36 (2) 37 (4) 42 (4) 41 (2) 40 (1)
avCO2 diff
[mmHg]
GP 6 (2) 10 (4)* 9 (3)#2 6 (3)#2 10 (10)
BEL 6 (3) 12 (3)* 9 (2)#3 8 (3)#3 8 (3)
Control 6 (4) 15 (3)* 18 (3)*#2,3 18 (3)*#2,3 13 (3)*
avO2 diff
[mmHg]
GP 142 (17) 134 (57) 130 (14) 139 (14) 123 (32)
BEL 143 (17) 142 (39) 146 (15) 154 (17) 146 (21)
Control 143 (8) 131 (25) 130 (29) 153 (11) 155 (18)
lactate
[mmol/l]
GP 1,2 (0,5) 2,8 (1,5)* 2,9 (1,1)* 1,5 (0,6) 0,9 (0,3)
BEL 1,3 (0,5) 3,2 (1,2)* 2,8 (0,9)* 1,4 (0,4) 1,1 (0,3)
Control 1 (0,1) 3,2 (0,7)* 3,3 (0,)* 2,1 (0,6) 1,8 (0,5)
PaO2
[mmHg]
GP 191 (16) 185 (28) 180 (28) 181 (11) 166 (25)*
BEL 190 (16) 166 (40)* 187 (18) 190 (20) 182 (20)
Control 166 (23) 151 (34) 178 (7) 177 (12) 184 (15)
PaO2/FiO2
[mmHg]
GP 472 (42) 417 (140) 455 (67) 414 (115) 411 (69)
BEL 474 (40) 415 (99) 468 (45) 475 (50) 454 (51)
Control 465 (7) 380 (70) 395 (67) 460 (28) 459 (38)
Ppeak
[cm H2O]
GP 17 (3) 17 (2) 18 (3)#2 19 (3)#2 19 (2)#2
BEL 17 (2) 19 (2) 17 (1)#3 17 (1)#3 18 (2)#3
Control 18 (0) 19 (1) 23 (8)*#2,3 24 (7)*#2,3 24 (7)*#2,3
Pmean
[cm H2O]
GP 8 (1) 8 (1) 8 (1) 8 (1) 8 (1)
BEL 9 (1) 9 (1) 9 (1) 9 (1) 9 (0)
Control 9 (0) 10 (1) 9 (1) 9 (1) 9 (1)
PEEP
[cm H2O]
GP 4 (1) 4 (1) 4 (1) 4 (1) 4 (1)
BEL 4 (0) 4 (0) 4 (0) 4 (0) 4 (0)
Control 4 (0) 4 (0) 4 (0) 4 (0) 4 (0)
AaDO2
[mmHg]
GP 48 (18) 70 (51) 57 (18) 72 (50) 69 (29)
BEL 51 (14) 75 (40) 47 (17) 47 (20) 56 (20)
Control 57 (2) 90 (24) 78 (31) 54 (14) 54 (16)
MV
[l/min]
GP 5.2 (1.2)#1,2 5.1 (1.1)#1,2 5.5 (1.6)#1 5.7 (0.8) 5.6 (1)#1,2
BEL 7.0 (1.0)#1 6.9 (0.8)#1 6.9 (0.8)#1 6.9 (0.8) 6.9 (0.8)#1
Control 7.0 (0.2)#2 6.8 (0.5)#2 6.8 (0.5) 7.2 (0.8) 7.2 (0.8)#2
  1. MAP mean arterial pressure, HR heart rate, CO cardiac output, EVLWI extravascular lung water index, GEDI global endiastolic volume index, CVP central venous pressure, SpO 2 peripheral oxygen saturation, SvO 2 central venous saturation, BE base excess, PaCO 2 arterial partial pressure of carbon dioxide, avCO 2 diff arteriovenous carbon dioxide difference, avO 2 diff ateriovenous oxygen difference, PaO 2 arterial partial pressure of oxygen, PaO 2 /FiO 2 Horovitz index, P peak peak inspiratory pressure, P mean mean airway pressure, PEEP positive end-expiratory pressure, AaDO 2 alveolar-arterial oxygen difference, MV respiratory minute volume
  2. *indicates p < 0.05 vs. Baseline value. # indicates p < 0.05 in intergroup comparison (1 = colloid vs. BEL; 2 = colloid vs. sham; 3 = BEL vs. sham)