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Table 2 Comparison of the risk of morality between APAP group and control group

From: Long-term mortality of acetaminophen poisoning: a nationwide population-based cohort study with 10-year follow-up in Taiwan

Variable APAP group Control group IRR (95% CI) p-value
  n Death PY# Rate* n Death PY# Rate*   
All 3235 241 17,685.4 13.6 9705 94 55,497.5 1.7 8.1 (6.3–10.2) <0.001
Age (years)
 ≤20 385 9 2276.7 4.0 1155 1 6905.8 0.1 27.3 (3.5–215.5) 0.002
 21–39 2235 119 12,768.9 9.3 6705 23 39,663.3 0.6 16.1 (10.3–25.1) <0.001
 40–64 489 58 2259.2 25.7 1467 27 7358.4 3.7 7.0 (4.4–11.1) <0.001
 ≥ 65 126 55 380.5 144.5 378 43 15,670.0 27.4 5.3 (3.5–7.9) <0.001
Sex
 Male 895 121 4601.9 26.3 2685 43 14,969.4 2.9 9.2 (6.5–13.0) <0.001
 Female 2340 120 13,083.6 9.2 7020 51 40,528.1 1.3 7.3 (5.3–10.1) <0.001
Comorbidity†
 DM 124 37 397.6 93.1 313 23 1331.5 17.3 5.4 (3.2–9.1) <0.001
 CAD 149 48 540.2 88.9 317 26 1346.4 19.3 4.6 (2.9–7.4) <0.001
 Stroke 84 27 323.6 83.4 137 22 501.6 43.9 1.9 (1.1–3.3) 0.025
 HTN 248 71 912.0 77.9 666 47 2918.3 16.1 4.8 (3.3–7.0) <0.001
 Liver disease 396 54 1691.6 31.9 952 38 4633.6 8.2 3.9 (2.6–5.9) <0.001
 Renal disease 308 46 1338.5 34.4 633 18 3099.2 5.8 5.9 (3.4–10.2) <0.001
 Mental Disorder 1139 106 5379.8 19.7 1409 42 6831.1 6.2 3.2 (2.2–4.6) <0.001
 Cancer 75 28 249.1 112.4 145 13 683.1 19.0 5.9 (3.1–11.4) <0.001
Follow up period
 0–12 months 3235 104 3042.2 34.2 9705 20 9329.4 2.1 16.0 (9.9–25.7) <0.001
 1–2 year 2897 34 2761.6 12.3 8958 19 8576.6 2.2 5.6 (3.2–9.7) <0.001
  ≥ 2 year 2641 103 11,881.6 8.7 8236 55 37,591.5 1.5 5.9 (4.3–8.2) <0.001
  1. #PY, person-years. *Rate, per 1000 person-years. †Participant may have multiple comorbidities. APAP, acetaminophen; IRR, incidence rate ratio; CI, confidence interval; DM, diabetes mellitus; CAD, coronary artery disease; HTN, hypertension