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Table 2 Comparison of patient characteristics

From: Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury

Variable Coagulopathy   Non-Coagulopathy
Control (35.5–37.0 °C) n = 12 MTH (32.0–34.0 °C) n = 20 P-value Control (35.5–37.0 °C) n = 28 MTH (32.0–34.0 °C) n = 59 P-value
Age (years) 31 (21–55) 48 (25–58) 0.34 41 (23–57) 42 (20–55) 0.93
Male 9 (81.8) 18 (90.0) 0.60 16 (59.3) 36 (62.1) 0.82
Systolic blood pressure (mmHg) 162 (128–177) 138 (122–160) 0.15 142 (115–183) 143 (110–175) 0.88
Heart rate (beats/min) 77 (71–95) 94 (71–113) 0.34 86 (65–106) 85 (72–104) 0.94
Glasgow Coma Scale score 6 (5–7) 6 (4–7) 0.72 6 (5–7) 6 (4–7) 0.65
Unreactive pupil or pupils 5 (41.7) 9 (45.0) 1.00 12 (42.9) 25 (42.4) 1.00
Platelet counts (×104/mm3) 22.4 (18.7–29.3) 24.5 (16.8–29.2) 0.91 26.2 (16.7–29.8) 22.1 (17.1–26.2) 0.14
APTT (s) 42.8 (27.3–81.9) 44.9 (35.4–87.1) 0.73 27.4 (24.3–36.2) 28.9 (25.7–33.2) 0.58
FDP (μg/mL) 168 (88.1–200.5) 106 (92.4–142.2) 0.17 37.5 (12.3–47.9) 26 (16.5–55.6) 0.91
Fibrinogen (mg/dL) 228 (125–271) 189 (164–246) 0.94 203 (167–264) 199 (164–235) 0.49
TCDB classification    0.77    0.30
 Diffuse injury grade I 0 (0) 0 (0)   1 (3.6) 1 (1.7)  
 Diffuse injury grade II 5 (41.7) 6 (30.0)   8 (28.6) 17 (28.8)  
 Diffuse injury grade III 2 (16.7) 5 (25.0)   6 (21.4) 6 (10.2)  
 Diffuse injury grade IV 0 (0) 1 (5.0)   2 (7.1) 1 (1.7)  
Non-evacuated mass/Evacuated mass 0/5 1/7 0.81 0/11 4/30 0.56
Surgical operation for TBI 7 (58.3) 9 (47.4) 0.72 18 (64.3) 40 (67.8) 0.81
Injury severity score 25 (21–25) 34 (22–36) 0.08 22 (16–29) 25 (17–34) 0.36
 AIS score for head 5 (4–5) 4 (4–5) 0.50 4 (4–5) 4(4–5) 0.20
AIS score ≥ 4 for other organs 0 (0) 4 (20.0) 0.27 3 (10.7) 4 (6.8) 0.67
  1. Values are presented as n (%) or median (interquartile ranges, IQRs)
  2. MTH mild therapeutic hypothermia, AIS abbreviated injury score, TBI traumatic brain injury, CT computed tomography, FDP fibrin degradation products, TCDB Traumatic Coma Data Bank