Table 2 Comparison of patient characteristics
From: Therapeutic hypothermia in patients with coagulopathy following severe traumatic brain injury
Variable | Coagulopathy | Non-Coagulopathy | ||||
|---|---|---|---|---|---|---|
Control (35.5–37.0 °C) n = 12 | MTH (32.0–34.0 °C) n = 20 | P-value | Control (35.5–37.0 °C) n = 28 | MTH (32.0–34.0 °C) n = 59 | P-value | |
Age (years) | 31 (21–55) | 48 (25–58) | 0.34 | 41 (23–57) | 42 (20–55) | 0.93 |
Male | 9 (81.8) | 18 (90.0) | 0.60 | 16 (59.3) | 36 (62.1) | 0.82 |
Systolic blood pressure (mmHg) | 162 (128–177) | 138 (122–160) | 0.15 | 142 (115–183) | 143 (110–175) | 0.88 |
Heart rate (beats/min) | 77 (71–95) | 94 (71–113) | 0.34 | 86 (65–106) | 85 (72–104) | 0.94 |
Glasgow Coma Scale score | 6 (5–7) | 6 (4–7) | 0.72 | 6 (5–7) | 6 (4–7) | 0.65 |
Unreactive pupil or pupils | 5 (41.7) | 9 (45.0) | 1.00 | 12 (42.9) | 25 (42.4) | 1.00 |
Platelet counts (×104/mm3) | 22.4 (18.7–29.3) | 24.5 (16.8–29.2) | 0.91 | 26.2 (16.7–29.8) | 22.1 (17.1–26.2) | 0.14 |
APTT (s) | 42.8 (27.3–81.9) | 44.9 (35.4–87.1) | 0.73 | 27.4 (24.3–36.2) | 28.9 (25.7–33.2) | 0.58 |
FDP (μg/mL) | 168 (88.1–200.5) | 106 (92.4–142.2) | 0.17 | 37.5 (12.3–47.9) | 26 (16.5–55.6) | 0.91 |
Fibrinogen (mg/dL) | 228 (125–271) | 189 (164–246) | 0.94 | 203 (167–264) | 199 (164–235) | 0.49 |
TCDB classification | 0.77 | 0.30 | ||||
Diffuse injury grade I | 0 (0) | 0 (0) | 1 (3.6) | 1 (1.7) | ||
Diffuse injury grade II | 5 (41.7) | 6 (30.0) | 8 (28.6) | 17 (28.8) | ||
Diffuse injury grade III | 2 (16.7) | 5 (25.0) | 6 (21.4) | 6 (10.2) | ||
Diffuse injury grade IV | 0 (0) | 1 (5.0) | 2 (7.1) | 1 (1.7) | ||
Non-evacuated mass/Evacuated mass | 0/5 | 1/7 | 0.81 | 0/11 | 4/30 | 0.56 |
Surgical operation for TBI | 7 (58.3) | 9 (47.4) | 0.72 | 18 (64.3) | 40 (67.8) | 0.81 |
Injury severity score | 25 (21–25) | 34 (22–36) | 0.08 | 22 (16–29) | 25 (17–34) | 0.36 |
AIS score for head | 5 (4–5) | 4 (4–5) | 0.50 | 4 (4–5) | 4(4–5) | 0.20 |
AIS score ≥ 4 for other organs | 0 (0) | 4 (20.0) | 0.27 | 3 (10.7) | 4 (6.8) | 0.67 |