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Table 1 Patient baseline characteristics according to six-month outcome

From: Common intensive care scoring systems do not outperform age and glasgow coma scale score in predicting mid-term mortality in patients with spontaneous intracerebral hemorrhage treated in the intensive care unit

  All patients (n = 3218) Development (n = 1589) Validation (n = 1629) P-value* Survivors (n = 1691) Non-survivors (n = 1527) P-value†
Age, in years
  < 45 416 (13) 216 (14) 200 (12) 0.392 263 (16) 153 (10) <0.001
 45–75 2467 (77) 1202 (75) 1265 (78) 1283 (76) 1184 (78)
  > 75 335 (10) 171 (11) 164 (10) 145 (8) 190 (12)
Level of care hospital
 Secondary (Central) 866 (27) 435 (27) 431 (27) 0.557 295 (17) 571 (37) <0.001
 Tertiary (University) 2352 (73) 1154 (73) 1198 (73) 1396 (83) 956 (63)
Prior functional ability
 Independent 2917 (91) 1435 (90) 1482 (91) 0.515 1578 (93) 1339 (88) <0.001
 Dependent 301 (9) 154 (10) 147 (9) 113 (7) 188 (12)
GCS
 3 to 8 1999 (62) 992 (62) 1007 (62) 0.764 654 (39) 1345 (88) <0.001
 9 to 12 485 (15) 243 (15) 242 (15) 374 (22) 111 (7)
 13 to 15 734 (23) 354 (22) 380 (23) 663 (39) 71 (5)
 APACHE II 23 (16, 28) 23 (16, 28) 22 (16, 28) 0.311 17 (12, 23) 27 (23, 31) <0.001
 SAPS II 47 (30, 57) 47 (30, 58) 46 (30, 57) 0.466 33 (23, 46) 56 (48, 63) <0.001
 SOFA 7 (4, 9) 7 (4, 9) 7 (4, 9) 0.073 5 (3, 8) 8 (6, 10) <0.001
TISS-76‡
 Total score 73 (44, 143) 74 (44, 145) 72 (44, 141) 0.605 80 (44, 163) 68 (44, 122) <0.001
 Average score 28 (23, 33) 28 (23, 33) 28 (22, 32) 0.055 26 (21, 31) 29 (24, 34) <0.001
ICU admission characteristics
 Mechanical ventilation 2437 (76) 1213 (76) 1224 (75) 0.428 1052 (62) 1385 (91) <0.001
 Operative admission 1105 (34) 564 (36) 541 (33) 0.173 677 (40) 428 (28) <0.001
 Comorbidity 303 (9) 157 (10) 146 (9) 0.373 125 (7) 178 (12) <0.001
Length of stay, in days
 ICU 2 (1, 4) 2 (1, 4) 2 (1,4) 0.875 2 (1, 5) 1 (1, 3) <0.001
 Hospital 5 (2, 12) 5 (2,12) 5 (2,12) 0.502 8 (4, 15) 3 (1, 7) <0.001
Mortality
 ICU 695 (22) 345 (22) 350 (22) 0.876 NA 695 (46) NA
 Hospital 1139 (35) 559 (35) 580 (36) 0.801 NA 1139 (75) NA
 Six-month 1527 (48) 741 (47) 786 (48) 0.358 NA 1527 (100) NA
  1. Categorical variables are presented as n (%), all continuous variables were highly skewed and are therefore presented as median (IQR); APACHE II Acute Physiology And Chronic Health Evaluation II; GCS Glasgow Coma Scale; ICU intensive care unit; NA not available; SAPS II Simplified Acute Physiology Score II; SOFA Sequental Organ Failure Assessment; TISS-76 Therapeutic Intervention Scoring System 76. *Between development and validation cohorts. †Between the survivors and non-survivors. TISS-76 score calculations were done once each calendar day. The total score refers to the sum of all TISS score calculations during the ICU stay. The average score refers to the mean daily score