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Table 1 Patient characteristics of patients <70 and ≥70 years of age

From: The most commonly used disease severity scores are inappropriate for risk stratification of older emergency department sepsis patients: an observational multi-centre study

  Total cohort <70 years ≥70 years
Demographics
 N (%) 2280 1497 (65.7) 783 (34.3)
 Age, mean (SD) [1] 61.1 (17.0) 52.2 (13.6) 78.2 (6.2)
 Gender (male), n (%) [1] 1315 (57.7) 821 (54.8) 494 (63.1)
 Included at University Medical Centre, n (%) 1860 (81.6) 1271 (84.9) 589 (75.2)
Co-morbidities, n (%)
 COPD [2] 349 (15.3) 158 (10.6) 191 (24.4)
 Heart failure [1] 329 (14.4) 133 (8.9) 196 (25.0)
 Liver disease [1] 113 (5.0) 94 (6.3) 19 (2.4)
 Renal disease [1] 416 (18.2) 261 (17.4) 155 (19.8)
 Nursing home [2] 138 (6.1) 46 (3.1) 92 (11.7)
 Immune-compromised [2] 951 (41.7) 720 (48.1) 231 (29.5)
 Malignancy – [1] 253 (11.1) 155 (10.4) 98 (12.5)
 Malignancy + [3] 345 (15.1) 244 (16.3) 101 (12.9)
 DNR status (%) (6) 478 (21.0) 185 (12.4) 293 (37.4)
Suspected source of infection, n (%)
 Pulmonary 1059 (46.4) 620 (41.4) 439 (56.1)
 Urogenital 675 (29.6) 397 (26.5) 278 (35.5)
 Abdominal 396 (17.4) 273 (18.2) 123 (15.7)
 Skin 198 (8.7) 145 (9.7) 53 (6.8)
 Neurological 48 (2.1) 35 (2.3) 13 (1.7)
 other 396 (17.4) 301 (20.1) 95 (12.1)
Vital signs on admission
 Systolic blood pressure, mean (SD) (241) 131.9 (25.9) 129.8 (23.5) 135.7 (29.3)
 Heart rate, mean (SD) (45) 108.0 (20.3) 110.2 (19.7) 103.8 (20.9)
 Respiratory rate, mean (SD) (558) 24.0 (7.2) 22.83 (6.9) 25.73 (7.5)
 Oxygen saturation, mean (SD) (71) 95.2 (4.8) 95.8 (4.6) 94.1 (5.2)
 Temperature (°C), mean (SD) (94) 38.72 (1.11) 38.74 (1.06) 38.69 (1.20)
 Altered mental status n (%) (420) 370 (16.2) 161 (10.8) 209 (26.7)
Laboratory analysis on admission
 Lactate (mmol/l), median (IQR) (293) 1.9 (1.4–2.6) 1.8 (1.4–2.6) 2.0 (1.5–2.8)
 Platelets (×109/l), median (IQR) (41) 209 (151–280) 207 (148–279) 213.5 (156–286)
 INR median (IQR), (702) 1.1 (1–1.4) 1.1 (1.0–1.29) 1.2 (1.0–2.4)
 Creatinine (μg/l), median (IQR) [16] 87 (67–120) 83 (64–110) 95 (74–134)
 Urea (mmol/l), median (IQR) (40) 7.0 (5.1–10.2) 6.2 (4.6–8.8) 8.8 (6.6–12.5)
 Band cells >5%, n (%) 179 (7.9) 103 (6.9) 76 (9.7)
 Bilirubin (μmol/l), median (IQR) (349) 12 (8–19) 12 (8–18) 12 (9–20)
Treatment variables
 Time to antibiotics (min), median (IQR) [23] 103 (58–167) 109 (63–174) 91 (51–152)
 Fluid resuscitation (L during ED stay), median (IQR) 1 (0.5–1.5) 1 (0.5–1.5) 1 (0.5–1.5)
 Supplementary oxygen (L/min), median (IQR) (85) 3 (0–5) 2 (0–5) 3 (2–6)
  1. Missing values are shown in parentheses for every variable
  2. Abbreviations: COPD chronic obstructive pulmonary disease, DNR do not resuscitate, °C degrees Celsius, SD standard deviation, IQR interquartile range, L litre, min = minute