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Table 3 Fluid therapy

From: Effect of dextran-70 on outcome in severe sepsis; a propensity-score matching study

  Propensity score matched groups  
  Control, n = 245 Dextran, n = 245 P
  Median Q1 to Q3 Median Q1 to Q3  
Dextran-70, 60 mg/ml (ml)
 Day 1 0 0 to 0 1000 500 to 1000 <0.001
 Day 2 0 0 to 0 0 0 to 500 <0.001
 Day 3 0 0 to 0 0 0 to 0 <0.001
 Mean per daya 0 0 to 0 399 200 to 654 <0.001
Albumin 50 mg/ml (ml)
 Day 1 0 0 to 500 0 0 to 500 0.17
 Day 2 0 0 to 0 0 0 to 0 0.0.66
 Day 3 0 0 to 0 0 0 to 0 0.80
 Mean per day 99 0 to 253 50 0 to 219 0.03
Albumin 200 mg/ml (ml)
 Day 1 0 0 to 154 0 0 to 0 <0.001
 Day 2 0 0 to 100 0 0 to 0 0.24
 Day 3 0 0 to 100 0 0 to 81 0.71
 Mean per day 43 0 to 121 17 0 to 80 <0.001
Crystalloidsb (ml)
 Day 1 2100 533 to 4000 3025 2000 to 4200 <0.001
 Day 2 78 0 to 420 130 0 to 985 0.06
 Day 3 0 0 to 200 27 0 to 300 0.09
 Mean per day 1050 343 to 2104 1279 740 to 2162 0.13
Blood transfusion (ml)
 Day 1 0 0 to 328 250 0 to 600 <0.001
 Day 2 0 0 to 0 0 0 to 295 0.008
 Day 3 0 0 to 0 0 0 to 245 0.88
 Mean per day 57 0 to 244 174 0 to 320 <0.001
Fluids in, totalc (ml)
 Day 1 4261 1942 to 6323 5700 3999 to 7475 <0.001
 Day 2 2817 1852 to 3982 3699 2684 to 4645 <0.001
 Day 3 2444 1253 to 3322 2924 2088 to 3964 0.006
 Mean per day 3823 2413 to 4891 4544 3314 to 5600 <0.001
Urine output (ml)
 Day 1 1400 605 to 2545 1073 381 to 2076 0.009
 Day 2 2243 1049 to 3622 1931 829 to 3211 0.04
 Day 3 2640 1410 to 3850 2555 1025 to 3743 0.92
 Mean per day 2010 376 to 3044 2078 327 to 3007 0.97
Total fluid balanced (ml)
 Day 1 1989 0 to 4528 3516 1703 to 5732 <0.001
 Day 2 0 −627 to 1550 995 0 to 2617 <0.001
 Day 3 −1 −1361 to 323 −38 −896 to 841 0.11
 Mean per day 581 −82 to 2015 1022 204 to 2264 0.03
  1. The number of patients in the control group was: Day 1 = 245. Day 2 = 191. Day 3 = 138. Day 4 = 102. Day 5 = 79. The number of patients in the dextran group was: Day 1 = 245. Day 2 = 212. Day 3 = 175. Day 4 = 139. Day 5 = 124. The data were collected from the patient’s electronic charts. No missing values. The decreasing number of patients represents patients who died or were discharged from the ICU
  2. aMean per day represents mean fluid administration per day up to 5 days after admission. For patients with ICU-stay <5 days the mean per day was calculated for the length of stay
  3. bCrystalloids represents the sum of NaCl 9 mg/ml and Ringer’s Acetate
  4. cFluids in, total represents the sum of all enteral and parenteral administered fluids including blood products
  5. dInsensible perspiration not included