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Table 2 Main outcome variables

From: Effect of dextran-70 on outcome in severe sepsis; a propensity-score matching study

 

Propensity-matched groups

Relative risk (95% CI)

Absolute risk reduction (95% CI)

Pa

Outcome

Control n = 245

Dextran n = 245

   

AKIN maxb median (Q1-Q3c)

1 (0–3)

2 (0–3)

  

0.06

DAFd of RRT, median (Q1-Q3)

28 (0–28)

28 (0–28)

  

0.52

DAF of vasopressors, median (Q1-Q3)

25 (0–27)

24 (0–26)

  

0.96

DAF of mechanical ventilation, median (Q1-Q3)

24 (0–28)

22 (0–27)

  

0.44

RRTe, no (%)

46 (18.8)

53 (21.6)

1.15 (0.81 to 1.64)

−2.9% (−9.9 to 4.2%)

0.42

Bleeding episodesf, no (%)

35 (14)

45 (18)

1.29 (0.86 to 1.93)

−4.1% (−10.6 to 2.5%)

0.21

28-day mortality, no (%)

86 (35.1)

78 (31.8)

0.91 (0.71 to 1.17)

3.3% (−5.1 to 11.7%)

0.41

90-day mortality, no (%)

109 (44.5)

96 (39.2)

0.88 (0.71 to 1.08)

5.3% (−3.4 to 14.0%)

0.21

180-day mortality, no (%)

123 (50.2)

102 (41.6)

0.83 (0.68 to 1.01)

8.6% (−0.2 to 17.4%)

0.046

  1. aWilcoxon rang sum or McNemar’s test
  2. bMaximal Acute Kidney Injury Network classification score the first 10 days after admission
  3. cInterquartile range
  4. dDays Alive and Free
  5. eRenal Replacement Therapy
  6. fDefined by patients that received more than 3 units of packed red blood cells at any day the first 10 days after admission