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Table 5 Sensitivity, Specificity, and Positive (PPV) and Negative Predictive Values (NPV) for 30-day mortality by different stratification tools in the Emergency Department (n = 68 cases of deaths within 30 days among 1535 patients)

From: Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department

Stratification tool Ability to identify those who died Sensitivity Specificity PPV NPV
n (% of 68 cases) (95% CI) (95% CI) (95% CI) (95% CI)
Severe sepsis 19 (27.9%) 0.29 (0.18-0.41) 0.94 (0.92-0.95) 0.18 (0.12-0.24) 0.96 (0.95-0.97)
SIRS ≥ 2 42 (61.8%) 0.64 (0.51-0.75) 0.55 (0.53-0.58) 0.06 (0.05-0.07) 0.97 (0.96-0.98)
SIRS ≥ 2 (without leucocytes) 32 (45.6%) 0.48 (0.36-0.61) 0.70 (0.68-0.72) 0.07 (0.05-0.08) 0.97 (0.96-0.97)
qSOFA ≥2 8 (11.9%) 0.13 (0.05-0.25) 0.96 (0.95-0.97) 0.14 (0.07-0.23) 0.96 (0.96-0.96)
Red triage 14 (20.2%) 0.21 (0.12-0.32) 0.94 (0.92-0.95) 0.13 (0.08-0.19) 0.96 (0.96-0.96)
Orange triage 31 (45.6%) 0.46 (0.22-0.58) 0.61 (0.58-0.63) 0.05 (0.04-0.07) 0.96 (0.95-0.97)
≥ Orange triage 45 (66.1%) 0.66 (0.54-0.77) 0.54 (0.52-0.57) 0.06 (0.05-0.07) 0.97 (0.96-0.97)