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Table 5 Sensitivity, Specificity, and Positive (PPV) and Negative Predictive Values (NPV) for 30-day mortality by different stratification tools in the Emergency Department (n = 68 cases of deaths within 30 days among 1535 patients)

From: Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department

Stratification tool

Ability to identify those who died

Sensitivity

Specificity

PPV

NPV

n (% of 68 cases)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Severe sepsis

19 (27.9%)

0.29 (0.18-0.41)

0.94 (0.92-0.95)

0.18 (0.12-0.24)

0.96 (0.95-0.97)

SIRS ≥ 2

42 (61.8%)

0.64 (0.51-0.75)

0.55 (0.53-0.58)

0.06 (0.05-0.07)

0.97 (0.96-0.98)

SIRS ≥ 2 (without leucocytes)

32 (45.6%)

0.48 (0.36-0.61)

0.70 (0.68-0.72)

0.07 (0.05-0.08)

0.97 (0.96-0.97)

qSOFA ≥2

8 (11.9%)

0.13 (0.05-0.25)

0.96 (0.95-0.97)

0.14 (0.07-0.23)

0.96 (0.96-0.96)

Red triage

14 (20.2%)

0.21 (0.12-0.32)

0.94 (0.92-0.95)

0.13 (0.08-0.19)

0.96 (0.96-0.96)

Orange triage

31 (45.6%)

0.46 (0.22-0.58)

0.61 (0.58-0.63)

0.05 (0.04-0.07)

0.96 (0.95-0.97)

≥ Orange triage

45 (66.1%)

0.66 (0.54-0.77)

0.54 (0.52-0.57)

0.06 (0.05-0.07)

0.97 (0.96-0.97)