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Table 4 Sensitivity, Specificity, and Positive (PPV) and Negative Predictive Values (NPV) for 7-day mortality by different stratification tools in the Emergency Department (n = 26 cases of deaths within 7 days among 1535 patients)

From: Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department

Stratification tool

Ability to identify those who died within 7 days

Sensitivity

Specificity

PPV

NPV

n (% of 26 cases)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Severe sepsis

8 (30.8%)

0.31 (0.14-0.52)

0.93 (0.92-0.94)

0.07 (0.04-0.12)

0.98 (0.98-0.98)

SIRS ≥2

17 (65.4%)

0.65 (0.44-0.82)

0.55 (0.52-0.57)

0.03 (0.02-0.03)

0.99 (0.98-0.99)

SIRS ≥2 (without leukocytes)

15 (57.7%)

0.58 (0.36-0.76)

0.70 (0.67-0.72)

0.03 (0.02-0.04)

0.99 (0.98-0.99)

qSOFA ≥2

4 (15.4%)

0.16 (0.05-0.36)

0.96 (0.95-0.97)

0.07 (0.03-0.15)

0.98 (0.98-0.99)

Red triage

8 (30.8%)

0.31 (0.14-0.51)

0.93 (0.91-0.95)

0.07 (0.04-0.12)

0.99 (0.98-0.99)

Orange triage

8 (30.8%)

0.31 (0.14-0.52)

0.60 (0.58-0.63)

0.01 (0.00-0.02)

0.98 (0.98-0.99)

≥ Orange triage

16 (61.5%)

0.62 (0.41-0.80)

0.53 (0.51-0.56)

0.02 (0.01-0.03)

0.99 (0.98-0.99)