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Table 4 Sensitivity, Specificity, and Positive (PPV) and Negative Predictive Values (NPV) for 7-day mortality by different stratification tools in the Emergency Department (n = 26 cases of deaths within 7 days among 1535 patients)

From: Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department

Stratification tool Ability to identify those who died within 7 days Sensitivity Specificity PPV NPV
n (% of 26 cases) (95% CI) (95% CI) (95% CI) (95% CI)
Severe sepsis 8 (30.8%) 0.31 (0.14-0.52) 0.93 (0.92-0.94) 0.07 (0.04-0.12) 0.98 (0.98-0.98)
SIRS ≥2 17 (65.4%) 0.65 (0.44-0.82) 0.55 (0.52-0.57) 0.03 (0.02-0.03) 0.99 (0.98-0.99)
SIRS ≥2 (without leukocytes) 15 (57.7%) 0.58 (0.36-0.76) 0.70 (0.67-0.72) 0.03 (0.02-0.04) 0.99 (0.98-0.99)
qSOFA ≥2 4 (15.4%) 0.16 (0.05-0.36) 0.96 (0.95-0.97) 0.07 (0.03-0.15) 0.98 (0.98-0.99)
Red triage 8 (30.8%) 0.31 (0.14-0.51) 0.93 (0.91-0.95) 0.07 (0.04-0.12) 0.99 (0.98-0.99)
Orange triage 8 (30.8%) 0.31 (0.14-0.52) 0.60 (0.58-0.63) 0.01 (0.00-0.02) 0.98 (0.98-0.99)
≥ Orange triage 16 (61.5%) 0.62 (0.41-0.80) 0.53 (0.51-0.56) 0.02 (0.01-0.03) 0.99 (0.98-0.99)