Skip to main content

Advertisement

Table 3 Overview of analysed biomarkers

From: Can we rely on out-of-hospital blood samples? A prospective interventional study on the pre-analytical stability of blood samples under prehospital emergency medicine conditions

Biomarkers in alphabetic order Unit Number of measurements Mean of differences CI mean Upper limit of agreement CI upper limit of agreement Lower limit of agreement CI lower limit of agreement
Alpha-HBDH (Clotting Activator) U/l 133 −1,143 [−6.38; 4.095] 59,928 [50.857;69] −62,214 [−71.286; −53.142]
Alpha-HBDH (Lithium Heparin) U/l 133 6,474 [2.725; 10.223] 50,189 [43.695;56.682] −37,241 [−43.735; −30.748]
Antithrombin III U/l 128 −0,156 [−0.858; 0.546] 7,869 [6.653;9.085] −8,182 [−9.397; −6.966]
aPTT sec. 128 −0,049 [−0.318; 0.22] 3,029 [2.563;3.495] −3,128 [−3.594; −2.661]
Calcium mmol/l 129 0,004 [−0.001; 0.009] 0,063 [0.054;0.072] −0,055 [−0.064; −0.046]
Chloride mmol/l 131 −0,191 [−0.424; 0.042] 2,505 [2.102;2.909] −2,887 [−3.29; −2.483]
Creatin Kinase (CK) (Clotting Activator) U/l 133 0,15 [−0.977; 1.278] 13,301 [11.348;15.254] −13 [−14.954; −11.047]
Creatin Kinase (CK) (Lithium Heparin) U/l 133 −0,895 [−2.044; 0.255] 12,509 [10.518;14.5] −14,298 [−16.289; −12.307]
Creatinine mg/dl 134 −0,006 [−0.01; −0.001] 0,046 [0.039;0.054] −0,058 [−0.066; −0.05]
Fibrinogen mg/dl 128 2,438 [−3.973; 8.848] 75,743 [64.639;86.847] −70,868 [−81.972; −59.764]
Free Haemoglobin (Clotting Activator) mg/l 132 −0,606 [−2.528; 1.316] 21,718 [18.389;25.047] −22,93 [−26.259; −19.601]
Free Haemoglobin (Lithium Heparin) mg/l 128 −0,062 [−1.729; 1.604] 18,992 [16.106;21.878] −19,117 [−22.003; −16.231]
Glutamic Oxaloacetic Transaminase (GOT/AST) U/l 134 0,604 [0.207; 1.001] 5,252 [4.564;5.939] −4,043 [−4.73; −3.355]
Haemoglobin g/dl 131 0,005 [−0.033; 0.044] 0,45 [0.383;0.517] −0,439 [−0.506; −0.373]
INR   128 −0,003 [−0.009; 0.002] 0,059 [0.05;0.069] −0,066 [−0.075; −0.056]
Leukocytes 109/l 131 −0,005 [−0.067; 0.057] 0,713 [0.605;0.82] −0,722 [−0.829; −0.615]
Myoglobin μg/l 134 −2,336 [−4.019; −0.652] 17,367 [14.452;20.283] −22,039 [−24.954; −19.123]
Potassium mmol/l 129 0,017 [−0.013; 0.046] 0,355 [0.304;0.406] −0,321 [−0.372; −0.27]
Sodium mmol/l 129 0,227 [−0.011; 0.465] 2,956 [2.544;3.368] −2,502 [−2.914; −2.09]
Thrombocytes 109/l 131 6,443 [4.765; 8.12] 25,85 [22.944;28.755] −12,964 [−15.869; −10.059]
Troponin I (Lithium Heparin) μg/l 134 −0,009 [−0.016; −0.002] 0,072 [0.06;0.084] −0,091 [−0.103; −0.079]
  1. Means of differences, standard deviations and confidence intervals between Groups of immediate analysis and analysis after mechanical stress and time delay. The estimated means of differences are always negligible with a small 95%-CI, i.e. mechanical stress does not produce a systematic bias but only random inaccuracy