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Table 2 Demographics, comorbidities, region of infection and outcomes in patients with NF

From: The laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring: the diagnostic and potential prognostic role

 

LRINEC <6 (45%)

LRINEC ≥6 (55%)

P

Age, years (mean ± SD)

48 ± 15

53 ± 16

0.009

Males (%)

74

73

0.82

Diabetes Mellitus (%)

41.5

61.4

0.001

Kidney disease %

10

20

0.02

Hypertension%

28 (21.5)

74 (46.8)

0.001

Site of infection %

 Lower limbs

49

55

0.32

 Perineum & genitalia

35.3

34.8

0.92

 Abdominal and groin

12.0

8.7

0.34

 Chest & breast

3.0

2.5

0.78

 Face & neck

6.0

7.5

0.62

 Number of debridement

2.14 ± 1.5

2.09 ± 1.3

0.81

Number of antibiotics useda (%)

 ≤2

81 (78.6)

83 (56.8)

0.001 for all

 >2

22 (21.4)

63 (43.2)

 Hospital LOS; days

11 (2–115)

22 (2–129)

0.001

 intensive care LOS; days

5 (2–34)

7 (1–75)

0.01

 Septic shock (%)

15

37

0.001

 Mortality (%)

15

28.8

0.005

  1. aFrequently used antibiotics are Tazocin, Clindamycin, Meropenem and Agumentin