| Male | Female | CCI score 0 | CCI score > 1 | Age < 85 years | Age > 85 years | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | Fentanyl adm./n (patients) | Adjusted Relative Risk (95% CI)* | |
Housing, n = 1967 | ||||||||||||
Own home | 97/391 | 1 (reference) | 309/937 | 1 (reference) | 203/598 | 1 (reference) | 202/730 | 1 (reference) | 260/815 | 1 (reference) | 145/513 | 1 (reference) |
OHATI | 22/69 | 1.36 (0.87-2.13) | 51/141 | 1.28 (1.02-1.60) | 29/71 | 1.41 (1.01-1.95) | 44/139 | 1.27 (0.97-1.66) | 35/91 | 1.26 (0.95-1.69) | 38/119 | 1.26 (0.94-1.71) |
Institution | 25/136 | 1.10 (0.73-1.68) | 35/293 | 0.58 (0.43-0.80) | 17/140 | 0.55 (0.34-0.89) | 43/289 | 0.80 (0.59-1.07) | 25/163 | 0.67 (0.46-0.97) | 35/266 | 0.71 (0.51-0.99) |
BMI, n = 2140 | ||||||||||||
Normal | 69/303 | 1 (reference) | 215/748 | 1 (reference) | 139/454 | 1 (reference) | 34/120 | 1 (reference) | 164/545 | 1 (reference) | 120/506 | 1 (reference) |
Underweight | 10/27 | 1.03 (0.50-2.12) | 41/164 | 0.96 (0.73-1.26) | 17/71 | 0.94 (0.61-1.45) | 145/597 | 1.02 (0.74-1.41) | 23/84 | 0.91 (0.64-1.31) | 28/107 | 1.19 (0.82-1.74) |
Overweight | 44/198 | 0.81 (0.56-1.17) | 101/323 | 1.13 (0.94-1.35) | 67/206 | 1.07 (0.85-1.36) | 78/315 | 1.00 (0.79-1.26) | 93/308 | 0.99 (0.80-1.21) | 52/213 | 1.13 (0.86-1.50) |
Obesea | 29/124 | 1.11 (0.70-1.76) | 75/253 | 0.98 (0.74-1.29) | 47/144 | 1.00 (0.73-.138) | 57/233 | 1.06 (0.76-1.48) | 71/228 | 0.98 (0.75-1.30) | 33/149 | 1.21 (0.78-1.87) |
Fracture displacement, n = 1981 | ||||||||||||
Yes | 126/519 | 1 (reference) | 347/1198 | 1 (reference) | 221/705 | 1 (reference) | 252/1012 | 1 (reference) | 283/924 | 1 (reference) | 190/793 | 1 (reference) |
No | 16/75 | 0.99 (0.57-1.74) | 37/155 | 1.10 (0.83-1.44) | 19/91 | 0.88 (0.59-1.32) | 34/139 | 1.19 (0.87-1.63) | 34/127 | 1.12 (0.83-1.52) | 19/103 | 0.99 (0.63-1.56) |
Unspecified | 2/10 | 0.96 (0.27-3.21) | 11/24 | 1.43 (0.92-2.21) | 8/17 | 1.33 (0.81-2.17) | 5/17 | 1.29 (0.53-3.16) | 7/20 | 1.01 (0.57-1.77) | 6/14 | 1.87 (0.95-3.68) |
Type of fracture | ||||||||||||
Subtrochanteric | 22/60 | 1 (reference) 0.76 | 49/122 | 1 (reference) | 33/66 | 1 (reference) | 38/116 | 1 (reference) | 44/102 | 1 (reference) | 27/80 | 1 (reference) |
Pertrochanteric | 67/276 | (0.49-1.16) | 190/596 | 0.93 (0.73-1.20) | 114/353 | 0.71 (0.52-0.96) | 143/519 | 0.79 (0.58-1.07) | 134/444 | 0.81 (0.61-1.06) | 123/428 | 0.89 (0.62-1.28) |
Medial | 63/316 | 0.70 (0.45-1.09) | 49/122 | 0.77 (0.60-0.99) | 123/456 | 0.84 (0.62-1.14) | 133/630 | 0.92 (0.68-1.25) | 173/619 | 0.75 (0.57-0.99) | 83/467 | 0.66 (0.45-0.96) |
Prior consultation with GP | ||||||||||||
No | 116/302 | 1 (reference) | 366/1134 | 1 (reference) | 234/678 | 1 (reference) | 259/944 | 1 (reference) | 303/923 | 1 (reference) | 190/699 | 1 (reference) |
Yes | 8/60 | 0.56 (0.33-0.92) | 66/354 | 0.91 (0.73-1.14) | 36/197 | 0.75 (0.54-1.04) | 55/321 | 0.87 (0.67-1.14) | 48/242 | 0.83 (0.63-1.10) | 43/276 | 0.71 (0.51-0.98) |
EMCC triage level | ||||||||||||
A (highest) | 17/45 | 1 (reference) | 39/88 | 1 (reference) | 32/68 | 1 (reference) | 23/77 | 1 (reference) | 42/106 | 1 (reference) | 13/39 | 1 (reference) |
B | 87/202 | 1.31 (0.84-2.06) | 317/897 | 0.88 (0.70-1.11) | 189/516 | 0.99 (0.76-1.28) | 221/730 | 1.08 (0.75-1.55) | 243/679 | 1.00 (0.77-1.29) | 167/567 | 0.97 (0.66-1.45) |
C | 10/72 | 0.68 (0.36-1.27) | 37/344 | 0.34 (0.23-0.50) | 19/190 | 0.32 (0.19-0.55) | 37/314 | 0.55 (0.34-0.88) | 32/241 | 0.47 (0.31-0.70) | 24/263 | 0.40 (0.23-0.72) |
Time with ambulance personnelb, minutes | ||||||||||||
<20 | 2/29 | 0.07 (0.01-0.51) | 0/125 | - | 3/67 | 0.04 (0.01-0.30) | 0/107 | - | 3/88 | 0.03 (0.01-0.21) | 0/86 | - |
20-29 | 8/47 | 0.28 (0.14-0.54) | 30/217 | 0.26 (0.18-0.39) | 20/126 | 0.31 (0.20-0.49) | 18/180 | 0.23 (0.14-0.38) | 27/162 | 0.32 (0.22-0.48) | 11/144 | 0.19 (0.10-0.35) |
30-39 | 15/52 | 0.62 (0.38-1.00) | 55/267 | 0.42 (0.32-0.55) | 39/146 | 0.53 (0.39-0.73) | 37/216 | 0.38 (0.26-0.54) | 44/183 | 0.46 (0.34-0.62) | 32/179 | 0.45 (0.31-0.65) |
40-49 | 23/57 | 0.83 (0.56-1.23) | 78/255 | 0.59 (0.47-0.74) | 49/161 | 0.64 (0.48-0.85) | 64/216 | 0.65 (0.50-0.85) | 65/196 | 0.63 (0.49-0.81) | 48/181 | 0.64 (0.47-0.89) |
50-59 | 24/62 | 0.78 (0.51-1.19) | 103/236 | 0.82 (0.67-0.99) | 59/143 | 0.81 (0.62-1.04) | 69/194 | 0.82 (0.64-1.06) | 74/189 | 0.72 (0.58-0.91) | 54/148 | 0.96 (0.73-1.28) |
>60 | 41/71 | 1 (reference) | 121/218 | 1 (reference) | 68/124 | 1 (reference) | 90/198 | 1 (reference) | 100/198 | 1 (reference) | 58/124 | 1 (reference) |
Yearc | ||||||||||||
2011 | 20/106 | 1 (reference) | 51/254 | 1 (reference) | 36/163 | 1 (reference) | 35/197 | 1 (reference) | 47/211 | 1 (reference) | 24/149 | 1 (reference) |
2012 | 61/240 | 1.44 (0.85-2.44) | 167/533 | 1.47 (1.10-1.96) | 106/307 | 1.60 (1.12-2.31) | 122/466 | 1.24 (0.87-1.78) | 145/427 | 1.43 (1.07-1.92) | 83/346 | 1.47 (0.89-2.43) |
2013 | 51/211 | 1.23 (0.72-2.11) | 139/455 | 1.50 (1.12-2.01) | 81/257 | 1.49 (1.02-2.17) | 109/409 | 1.30 (0.91-1.87) | 109/350 | 1.33 (0.98-1.81) | 81/316 | 1.61 (0.98-2.64) |
2014 | 20/95 | 1.48 (0.79-2.76) | 75/246 | 1.55 (1.13-2.13) | 47/148 | 1.60 (1.06-2.41) | 48/193 | 1.37 (0.91-2.04) | 50/177 | 1.28 (0.90-1.81) | 45/164 | 1.96 (1.16-3.31) |
Sex | ||||||||||||
Female | - | - | - | - | 210/666 | 1 (reference) | 222/822 | 1 (reference) | 260/764 | 1 (reference) | 172/724 | 1 (reference) |
Male | Â | Â | Â | Â | 60/209 | 0.83 (0.64-1.07) | 92/443 | 0.71 (0.56-0.90) | 91/401 | 0.70 (0.56-0.87) | 61/251 | 0.89 (0.67-1.19) |
CCI score | ||||||||||||
0 | 60/209 | 1 (reference) | 210/666 | 1 (reference) | - | - | - | - | 159/433 | 1 (reference) | 111/442 | 1 (reference) |
1 | 31/155 | 0.63 (0.41-0.97) | 93/373 | 0.82 (0.66-1.02) | Â | Â | Â | Â | 70/287 | 0.69 (0.54-0.90) | 54/241 | 0.87 (0.65-1.16) |
2 | 29/121 | 0.80 (0.54-1.19) | 56/219 | 0.82 (0.63-1.07) | Â | Â | Â | Â | 52/204 | 0.79 (0.61-1.04) | 33/136 | 0.94 (0.65-1.37) |
3+ | 32/167 | 0.66 (0.44-1.00) | 73/230 | 1.00 (0.81-1.24) | Â | Â | Â | Â | 70/204 | 0.87 (0.69-1.10) | 35/156 | 0.88 (0.63-1.24) |
Age, years | ||||||||||||
65-74 | 37/144 | 1 (reference) | 87/218 | 1 (reference) | 67/155 | 1 (reference) | 57/207 | 1 (reference) | - | - | - | - |
75-79 | 26/108 | 0.85 (0.53-1.38) | 78/230 | 0.92 (0.72-1.18) | 37/115 | 0.71 (0.50-1.01) | 67/223 | 1.08 (0.80-1.45) | Â | Â | Â | Â |
80-84 | 28/149 | 0.64 (0.40-1.04) | 95/316 | 0.84 (0.66-1.06) | 55/163 | 0.78 (0.58-1.05) | 68/302 | 0.78 (0.56-1.08) | Â | Â | Â | Â |
85-89 | 45/158 | 0.94 (0.63-1.40) | 82/369 | 0.65 (0.50-0.84) | 58/219 | 0.61 (0.45-0.84) | 69/308 | 0.81 (0.59-1.12) | Â | Â | Â | Â |
>90 | 16/93 | 0.59 (0.32-1.11) | 90/355 | 0.86 (0.68-1.09) | 53/223 | 0.76 (0.57-1.01) | 53/225 | 0.90 (0.65-1.28) | Â | Â | Â | Â |