Table 1 Grading of anaphylaxis according to severity of clinical symptoms. Sampson 2003

1

Localized pruritus, flushing, urticaria, angioedema

Oral pruritus, oral “tingling”, mild lip swelling

2

Generalized pruritus, urticaria, angioedema

Any of the above, nausea and/or emesis x’s 1

Nasal congestion and/or sneezing

Change in activity level

3

Any of the above

Any of the above, plus repetitive vomiting

Rhinorrhea, marked congestion, sensation of throat pruritus or tightness

Tachycardia (increase >15 beats/min)

Change in activity level plus anxiety

4

Any of the above

Any of the above plus diarrhea

Any of the above, hoarseness, “barky” cough, difficulty swallowing, dyspnea, wheezing, cyanosis

Any of the above, dysrhythmia and/or mild hypotension

“Light headedness” feeling of “pending doom”

5

Any of the above

Any of the above, loss of bowel control

Any of the above, respiratory arrest

Severe bradycardia and/or hypotension or cardiac arrest

Loss of consciousness