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Table 3 Sensitivity and specificity of LT-BI according to the combination of pSBP and pHR

From: Impact of Cushing’s sign in the prehospital setting on predicting the need for immediate neurosurgical intervention in trauma patients: a nationwide retrospective observational study

   Sensitivity (95% CI) Specificity (95% CI)
pSBP ≤ 99 pHR ≤ 59 0.011 (0.007–0.015) 0.985 (0.984–0.987)
60 ≤ pHR ≤ 99 0.042 (0.035–0.052) 0.900 (0.896–0.903)
100 ≤ pHR ≤ 139 0.030 (0.023–0.037) 0.931 (0.928–0.934)
140 ≤ pHR 0.006 (0.004–0.010) 0.989 (0.988–0.991)
100 ≤ pSBP ≤ 139 pHR ≤ 59 0.034 (0.028–0.041) 0.975 (0.973–0.978)
60 ≤ pHR ≤ 99 0.190 (0.175–0.206) 0.706 (0.700–0.713)
100 ≤ pHR ≤ 139 0.065 (0.056–0.076) 0.885 (0.881–0.889)
140 ≤ pHR 0.006 (0.003–0.010) 0.990 (0.989–0.992)
140 ≤ pSBP ≤ 179 pHR ≤ 59 0.042 (0.036–0.049) 0.982 (0.979–0.985)
60 ≤ pHR ≤ 99 0.231 (0.215–0.246) 0.829 (0.823–0.836)
100 ≤ pHR ≤ 139 0.072 (0.062–0.082) 0.928 (0.924–0.932)
140 ≤ pHR 0.009 (0.006–0.013) 0.989 (0.988–0.991)
180 ≤ pSBP pHR ≤ 59 0.023 (0.018–0.026) 0.994 (0.993–0.996)
60 ≤ pHR ≤ 99 0.178 (0.166–0.189) 0.946 (0.941–0.951)
100 ≤ pHR ≤ 139 0.055 (0.047–0.063) 0.972 (0.968–0.975)
140 ≤ pHR 0.006 (0.004–0.008) 0.997 (0.996–0.998)
  1. LT-BI life-threatening brain injuries requiring immediate neurosurgical intervention, pSBP systolic blood pressure in the prehospital setting, pHR heart rate in the prehospital setting