Table 7 Univariate and multivariate analyses evaluating the association of Δchloride (mmol/L) on 30-day mortality

Age (per year)

1.014 (0.994–1.034)

0.17

.

ISS

1.080 (1.033–1.130)

0.001

.

RTS

0.621 (0.511–0.754)

<0.001

0.728 (0.559–0.950)

0.02

Mechanical ventilation (yes)

21.838 (2.929–162.842)

0.003

.

Transfusion (yes)

6.750 (2.290–19.894)

0.001

.

Hypotension (SBP < 90mmHg, yes)

4.477 (1.971–10.168)

<0.001

.

Hypothermia (BT < 35 °C, yes)

3.828 (1.626–9.012)

0.002

.

Cumulative fluid balance at 48 h (per L)

1.000 (1.000–1.000)^a

0.01

.

Base deficit at 48 h (per 1 mmol/L)

0.740 (0.631–0.868)

<0.001

0.761 (0.631–0.918)

0.004

Δchloride (per 1 mmol/L)

1.165 (1.096–1.238)

<0.001

1.096 (1.027–1.169)

0.006

Use of vasopressor (yes)

29.186 (6.789–125.472)

<0.001

10.392 (2.222–48.604)

0.003

Use of loop diuretics (yes)

3.243 (1.432–7.344)

0.005

.

AKI (yes)

7.130 (3.112–16.336)

<0.001

.