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Table 7 Univariate and multivariate analyses evaluating the association of Δchloride (mmol/L) on 30-day mortality

From: Hyperchloremia is associated with 30-day mortality in major trauma patients: a retrospective observational study

Variables Univariate analysis Multivariate analysis
OR (95 % CI) p value OR (95 % CI) p value
Age (per year) 1.014 (0.994–1.034) 0.17 .  
ISS 1.080 (1.033–1.130) 0.001 .  
RTS 0.621 (0.511–0.754) <0.001 0.728 (0.559–0.950) 0.02
Mechanical ventilation (yes) 21.838 (2.929–162.842) 0.003 .  
Transfusion (yes) 6.750 (2.290–19.894) 0.001 .  
Hypotension (SBP < 90mmHg, yes) 4.477 (1.971–10.168) <0.001 .  
Hypothermia (BT < 35 °C, yes) 3.828 (1.626–9.012) 0.002 .  
Cumulative fluid balance at 48 h (per L) 1.000 (1.000–1.000)a 0.01 .  
Base deficit at 48 h (per 1 mmol/L) 0.740 (0.631–0.868) <0.001 0.761 (0.631–0.918) 0.004
Δchloride (per 1 mmol/L) 1.165 (1.096–1.238) <0.001 1.096 (1.027–1.169) 0.006
Use of vasopressor (yes) 29.186 (6.789–125.472) <0.001 10.392 (2.222–48.604) 0.003
Use of loop diuretics (yes) 3.243 (1.432–7.344) 0.005 .  
AKI (yes) 7.130 (3.112–16.336) <0.001 .  
  1. OR odds ratio, CI confidence interval, ISS injury severity score, RTS revised trauma score, AKI acute kidney injury, SBP systolic blood pressure, BT body temperature, AKI acute kidney injury
  2. a(1.000027–1.000216)
  3. p value for the Hosmer-Lemeshow goodness-of-fit-test was 0.835