Rewarming technique | Rewarming rate | Notes & controversies | Rewarming complications |
---|---|---|---|
PASSIVE REWARMING [79] | |||
Passive rewarming | 0.5–4 °C hr-1 (dependent upon patient’s thermoregulatory function and metabolic reserves) [79, 242]. | Protect from further heat loss and allow patient to self-rewarm. Minimal controversy for mild hypothermia if the patient is able to self-rewarm. | Negligible in isolated mild hypothermia. For colder patients and those with secondary hypothermia or comorbid illness, there may be morbidity associated with a prolonged rewarming process if the patient has poor tolerance for the hypothermia-induced organ dysfunction (i.e. hypotension, coagulopathy, arrhythmias, impaired cellular function etc.). |
Passive rewarming with active movement | 1–5 °C hr-1 | Exercise has been shown to increase afterdrop in physiology studies from ~0.3 °C in controls to ~1 °C in exercised subjects, however the exercised subjects rewarmed more quickly [243]. | No reported complications. Some authors highlight the theoretical risk that the slightly increased afterdrop could contribute to morbidity and mortality. No adverse events were noted [243]. |
ACTIVE EXTERNAL REWARMING | |||
Active rewarming e.g. forced air surface [244] Arctic Sun® [245–247] | 0.5-4 °C hr-1 | Protect from further heat loss, deliver external heat and (if required) warmed IV fluids. Minimal controversies. | Similar to passive rewarming. |
ACTIVE INTERNAL REWARMING | |||
Bladder lavage | Variable. Adds ~0.5–1 °C hr-1 | Helpful if rewarming rate is slow. Minimal controversies. Rewarming is intermittent & slow because of small surface area. Poor control of infusate temperature [242, 248, 249]. | Negligible unless difficult catheterization. |
Gastric lavage | Adds ~0.5–1 °C hr-1 | Not commonly used due to risk vs. benefit ratio [249]. | Potential for aspiration, fluid & electrolyte shifts. |
Intravascular catheter rewarming e.g. Icy® catheter (CoolGuard®) [76, 250–252] | Device specific (adds ~0.5–2.5 °C hr-1) | Uncertain indication for use, potential for benefit exists in colder and sicker co-morbid patients with stable circulation. | Potential for haemorrhage or thrombosis, potentially worsening hypotension in unstable patients. |
Adds ~1–2 °C hr-1 | Not commonly used unless patient is unstable and ECLS rewarming is not available. | Potential for haemorrhage, lung or bowel trauma, fluid & electrolyte shifts. Thoracic lavage has the potential to impair CPR quality. | |
Adds ~1.5–3 °C hr-1 | Not commonly used unless ECLS rewarming not available. Requires adequate blood pressure. Heparinisation required. | Problems rare. Local vascular complications. Air embolism. Hypotension. | |
Adds ~2–3 °C hr-1 | Not commonly used, patient must be able to increase cardiac output to perfuse the external circuit. Heparinisation required. | Potential for hypotension, haemorrhage, thrombosis, haemolysis, etc. | |
Veno-venous rewarming (usually with an ECMO circuit) [248] | ~4–10 °C hr-1 | Not commonly used. Provides no circulatory or ventilatory support in case of cardiac arrest. Patient must be able to increase cardiac output to provide circuit perfusion. | Potential for hypotension, haemorrhage, thrombosis, haemolysis, etc. |
Extra-corporeal life support (VA-ECMO or CPB) | ~4–10 °C hr-1 | Preferred rewarming method for patients in cardiac arrest. CPB can use femoral route avoiding need for sternotomy [1, 42] | Potential for haemorrhage, thrombosis, haemolysis, etc. (as with all intravascular devices). |