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Table 1 Physiological changes with PLR

From: The assessment of circulating volume using inferior vena cava collapse index and carotid Doppler velocity time integral in healthy volunteers: a pilot study

Measurement/Indicator Mean ± (SD) legs flat Mean ± (SD) legs raised % change of mean with PLR Mean difference p value
Pulse rate 61 ± (10) 60 ± (9) -1.6 % -1 (95 % CI -3 : +1) >0.05
Respiratory rate 15 ± (2) 15 ± (2) 0.0 % 0 (95 % CI -1 : +1) >0.05
Systolic blood pressure 115 ± (11) 107 ± (10) -7.0 % -8 (95 % CI -11 : -5) >0.05
Diastolic blood pressure 72 ± (8) 65 ± (8) -9.7 % -7 (95 % CI -10 : -4) >0.05
IVC-CI - quiet respiration 0.24 ± (0.12) 0.17 ± (0.10) -29.2 % -0.06 (95 % CI -0.10; -0.02) <0.01
IVC-CI - sniff 0.57 ± (0.23) 0.42 ± (0.26) -26.3 % -0.15 (95 % CI -0.25; -0.06) <0.01
Stroke volume (mL) 56.0 ± (13.0) 69.2 ± (14.2) +23.6 % +13.2 (95 % CI +9.6 : +16.7) <0.01
Cardiac output (L/min) 3.3 ± (0.80) 4.1 ± (0.88) +22.3 % +0.75 (95 % CI +0.55; +0.96) <0.001
Common carotid flow (mL/min) 770 ± (202) 773 ± (167) +0.3 % +3 (95 % CI -37 : +43) >0.05
  1. Changes in values of pulse rate, respiratory rate, blood pressure, cardiac output, IVCCI and carotid blood flow with PLR