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Table 1 Physiological changes with PLR

From: The assessment of circulating volume using inferior vena cava collapse index and carotid Doppler velocity time integral in healthy volunteers: a pilot study

Measurement/Indicator

Mean ± (SD) legs flat

Mean ± (SD) legs raised

% change of mean with PLR

Mean difference

p value

Pulse rate

61 ± (10)

60 ± (9)

-1.6 %

-1 (95 % CI -3 : +1)

>0.05

Respiratory rate

15 ± (2)

15 ± (2)

0.0 %

0 (95 % CI -1 : +1)

>0.05

Systolic blood pressure

115 ± (11)

107 ± (10)

-7.0 %

-8 (95 % CI -11 : -5)

>0.05

Diastolic blood pressure

72 ± (8)

65 ± (8)

-9.7 %

-7 (95 % CI -10 : -4)

>0.05

IVC-CI - quiet respiration

0.24 ± (0.12)

0.17 ± (0.10)

-29.2 %

-0.06 (95 % CI -0.10; -0.02)

<0.01

IVC-CI - sniff

0.57 ± (0.23)

0.42 ± (0.26)

-26.3 %

-0.15 (95 % CI -0.25; -0.06)

<0.01

Stroke volume (mL)

56.0 ± (13.0)

69.2 ± (14.2)

+23.6 %

+13.2 (95 % CI +9.6 : +16.7)

<0.01

Cardiac output (L/min)

3.3 ± (0.80)

4.1 ± (0.88)

+22.3 %

+0.75 (95 % CI +0.55; +0.96)

<0.001

Common carotid flow (mL/min)

770 ± (202)

773 ± (167)

+0.3 %

+3 (95 % CI -37 : +43)

>0.05

  1. Changes in values of pulse rate, respiratory rate, blood pressure, cardiac output, IVCCI and carotid blood flow with PLR