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Table 1 Characteristics according to randomization group during the cooling and ECLS rewarming phase

From: Cardiopulmonary responses during the cooling and the extracorporeal life support rewarming phases in a porcine model of accidental deep hypothermic cardiac arrest

  

Cooling phase

ECLS rewarming phase

  

Baseline

32

30

25

20

20

25

30

35

LF group

HR, beats/min

100 ± 5

84 ± 9

70 ± 5

55 ± 4

29 ± 9

  

88 ± 15

124 ± 6

 

AP, mmHg

72 ± 7

70 ± 4

44 ± 4

29 ± 2

19 ± 4

27 ± 3*

35 ± 3*

70 ± 9

63 ± 8

 

PAP, mmHg

20 ± 2

28 ± 7

24 ± 3

19 ± 3

13 ± 2

8 ± 1

11 ± 2

19 ± 3

33 ± 3

 

PVR, dyn · s · cm−5

234 ± 50

 

487 ± 132

515 ± 139

   

800 ± 419

951 ± 229

 

EtCO2, mmHg

42 ± 4

27 ± 1

29 ± 1.3

24 ± 2

23 ± 1

11 ± 2

5 ± 1

16 ± 3

33 ± 3

 

CO, L/min

4.4 ± .4

3.3 ± .4

2.8 ± .3

2.3 ± .5

   

1.4 ± .3&

2.7 ± .5

 

pH

7.40 ± .02

7.43 ± .02

7.39 ± .03

7.35 ± .04

7.18 ± .02

7.28 ± .04

7.36 ± .06

7.35 ± .05

7.38 ± .04

 

PO2/FiO2, mmHg

449 ± 40

598 ± 69

547 ± 68

549 ± 74

523 ± 191

386 ± 78

934 ± 145

480 ± 118

398 ± 123

 

PCO2, mmHg

51 ± 3

40 ± 2

46 ± 3

49 ± 5

56 ± 10

54 ± 6

47 ± 6

43 ± 5

37 ± 3

 

Serum lactate, mmol/L

2.09 ± .21

    

7.66 ± 1.55

  

5.44 ± .54*

 

Serum potassium, mmol/L

3.87 ± .15

    

3.97 ± .13

  

3.77 ± .17

NF group

HR, beats/min

107 ± 9

80 ± 6

68 ± 6

51 ± 5

25 ± 10

  

91 ± 9

138 ± 9

 

AP, mmHg

68 ± 3

66 ± 5

46 ± 5

28 ± 3

20 ± 1

41 ± 3*

48 ± 3*

64 ± 6

74 ± 7

 

PAP, mmHg

21 ± 3

32 ± 15

20 ± 2

16 ± 2

15 ± 6

11 ± 1

12 ± 1

18 ± 3

29 ± 3

 

PVR, dyn · s · cm−5

287 ± 55

 

461 ± 54

453 ± 121

   

480 ± 208

499 ± 93

 

EtCO2, mmHg

42 ± 4

25 ± 4

26 ± 2

22 ± 2

19 ± 3

11 ± 2

7 ± 2

12 ± 3

30 ± 4

 

CO, L/min

4.4 ± .4

3.0 ± .4

2.5 ± .2

1.9 ± .1

   

1.7 ± .6&

3.9 ± .5

 

pH

7.40 ± .02

7.45 ± .14

7.41 ± .04

7.38 ± .03

7.34 ± .01

7.33 ± .03

7.27 ± .03

7.37 ± .03

7.39 ± .03

 

PO2/FiO2, mmHg

433 ± 52

514 ± 164

574 ± 51

684 ± 85

369 ± 45

344 ± 35

783 ± 158

755 ± 103

382 ± 59

 

PCO2, mmHg

49 ± 3

43 ± 16

43 ± 4

46 ± 3

48 ± 3

52 ± 5

51 ± 3

38 ± 3

33 ± 3

 

Serum lactate, mmol/L

2.27 ± .20

    

5.30 ± .86

  

3.91 ± .50*

 

Serum potassium, mmol/L

3.96 ± .08

    

3.99 ± .16

  

3.76 ± .17

  1. Groups: LF/low blood flow rate of 1.5 L/min; NF/normal blood flow rate of 3 L/min. PaO 2 /FiO 2 arterial oxygen pressure/inspired oxygen fraction, ABP arterial blood pressure, PAP pulmonary arterial pressure, PVR pulmonary vascular resistance. Values are presented as mean ± SEM. & measured only on 6 pigs in each group that achieved ROSC at this time point. * p < 0.05 compared with the other group