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Table 2 Blood gas in animals at baseline and after sea water drowning

From: Continuous venovenous hemofiltration decreases mortality and ameliorates acute lung injury in canine model of severe salt water drowning

  Baseline 15 min 60 min 120 min 180 min 240 min
pH
 Control 7.35 ± 0.03 7.23 ± 0.03* 7.22 ± 0.20* 7.21 ± 0.12* 7.18 ± 0.10* 7.16 ± 0.10*
 CVVH 7.37 ± 0.05 7.22 ± 0.09* 7.34 ± 0.08# 7.34 ± 0.06# 7.36 ± 0.05# 7.40 ± 0.08#
P a CO 2 (mmHg)
 Control 35.1 ± 1.21 35.17 ± 3.67 40.48 ± 7.03* 43.28 ± 5.21* 40.7 ± 5.14* 40.68 ± 5.83*
 CVVH 34.5 ± 2.32 31.53 ± 7.13 33.13 ± 8.29 37.23 ± 3.18 39.33 ± 7.35 38.22 ± 8.11
P a O 2 (mmHg)
 Control 102.4 ± 4.03 33.5 ± 4.03* 58.2 ± 11.2* 61.2 ± 8.67* 61.8 ± 10.0* 65.2 ± 7.88*
 CVVH 101.0 ± 2.73 36.4 ± 8.98* 61.6 ± 4.93* 68.1 ± 10.0* 76.0 ± 5.98* # 86.5 ± 4.72#
AB (mmol/L)
 Control 21.4 ± 3.2 15.9 ± 4.0* 16.1 ± 3.6* 15.9 ± 3.8* 15.7 ± 2.6* 15.7 ± 3.9*
 CVVH 22.1 ± 3.7 15.6 ± 3.4* 16.4 ± 4.1* 18.2 ± 2.4 19.9 ± 3.8# 21.5 ± 2.4#
BE (mmol/L)
 Control –4.1 ± 0.9 –11.2 ± 5.2* –11.1 ± 2.5* –11.9 ± 3.8* –12.3 ± 4.3* –13.1 ± 3.7*
 CVVH –4.8 ± 1.5 –11.7 ± 3.8* –9.3 ± 3.2* –7.1 ± 2.8# –5.2 ± 1.7# –4.7 ± 2.9#
S a O 2 (%)
 Control 97.5 ± 0.92 53.9 ± 7.33* 75.6 ± 8.75* 80.9 ± 7.24* 84.4 ± 6.58* 86.6 ± 5.98*
 CVVH 98.6 ± 0.58 50.2 ± 10.95* 86.6 ± 5.71 90.9 ± 4.33# 92.7 ± 4.62# 94.9 ± 3.49#
  1. Blood gas was determined in arterial blood samples from animals before and 15, 50, 120, 180, and 240 minutes after involuntary intratracheal sea water infusion. All animals received mechanical ventilation after sea water infusion and then were randomly divided into control and CRRT group *p < 0.05, vs, the same group of animals before infusion (baseline); #p < 0.05, vs, animals in control group at the same time point