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Table 2 Blood gas in animals at baseline and after sea water drowning

From: Continuous venovenous hemofiltration decreases mortality and ameliorates acute lung injury in canine model of severe salt water drowning

 

Baseline

15 min

60 min

120 min

180 min

240 min

pH

 Control

7.35 ± 0.03

7.23 ± 0.03*

7.22 ± 0.20*

7.21 ± 0.12*

7.18 ± 0.10*

7.16 ± 0.10*

 CVVH

7.37 ± 0.05

7.22 ± 0.09*

7.34 ± 0.08#

7.34 ± 0.06#

7.36 ± 0.05#

7.40 ± 0.08#

P a CO 2 (mmHg)

 Control

35.1 ± 1.21

35.17 ± 3.67

40.48 ± 7.03*

43.28 ± 5.21*

40.7 ± 5.14*

40.68 ± 5.83*

 CVVH

34.5 ± 2.32

31.53 ± 7.13

33.13 ± 8.29

37.23 ± 3.18

39.33 ± 7.35

38.22 ± 8.11

P a O 2 (mmHg)

 Control

102.4 ± 4.03

33.5 ± 4.03*

58.2 ± 11.2*

61.2 ± 8.67*

61.8 ± 10.0*

65.2 ± 7.88*

 CVVH

101.0 ± 2.73

36.4 ± 8.98*

61.6 ± 4.93*

68.1 ± 10.0*

76.0 ± 5.98* #

86.5 ± 4.72#

AB (mmol/L)

 Control

21.4 ± 3.2

15.9 ± 4.0*

16.1 ± 3.6*

15.9 ± 3.8*

15.7 ± 2.6*

15.7 ± 3.9*

 CVVH

22.1 ± 3.7

15.6 ± 3.4*

16.4 ± 4.1*

18.2 ± 2.4

19.9 ± 3.8#

21.5 ± 2.4#

BE (mmol/L)

 Control

–4.1 ± 0.9

–11.2 ± 5.2*

–11.1 ± 2.5*

–11.9 ± 3.8*

–12.3 ± 4.3*

–13.1 ± 3.7*

 CVVH

–4.8 ± 1.5

–11.7 ± 3.8*

–9.3 ± 3.2*

–7.1 ± 2.8#

–5.2 ± 1.7#

–4.7 ± 2.9#

S a O 2 (%)

 Control

97.5 ± 0.92

53.9 ± 7.33*

75.6 ± 8.75*

80.9 ± 7.24*

84.4 ± 6.58*

86.6 ± 5.98*

 CVVH

98.6 ± 0.58

50.2 ± 10.95*

86.6 ± 5.71

90.9 ± 4.33#

92.7 ± 4.62#

94.9 ± 3.49#

  1. Blood gas was determined in arterial blood samples from animals before and 15, 50, 120, 180, and 240 minutes after involuntary intratracheal sea water infusion. All animals received mechanical ventilation after sea water infusion and then were randomly divided into control and CRRT group *p < 0.05, vs, the same group of animals before infusion (baseline); #p < 0.05, vs, animals in control group at the same time point