| |
Baseline
|
15 min
|
60 min
|
120 min
|
180 min
|
240 min
|
|---|
|
mABP(mmHg)
|
|
Control
|
153 ± 22
|
127 ± 27*
|
124 ± 35*
|
125 ± 28*
|
118 ± 41*
|
113 ± 50*
|
|
CVVH
|
149 ± 25
|
128 ± 19*
|
126 ± 17*
|
132 ± 27
|
135 ± 15
|
134 ± 29
|
|
HR(beat/min)
|
|
Control
|
194 ± 29
|
132 ± 39*
|
139 ± 24*
|
128 ± 22*
|
122 ± 28*
|
120 ± 39*
|
|
CVVH
|
204 ± 33
|
146 ± 34*
|
134 ± 18*
|
136 ± 37*
|
138 ± 29*
|
128 ± 22*
|
|
CVP(cmH
2
O)
|
|
Control
|
9.91 ± 1.43
|
9.03 ± 1.78
|
10.18 ± 1.71
|
10.52 ± 1.23
|
10.21 ± 1.43
|
9.37 ± 2.15
|
|
CVVH
|
10.21 ± 2.62
|
9.73 ± 3.52
|
10.59 ± 4.28
|
11.19 ± 3.98
|
11.03 ± 4.87
|
11.28 ± 4.11
|
|
Osmolarity (mOs/kg)
|
|
Control
|
291 ± 11
|
313 ± 13*
|
311 ± 7*
|
307 ± 10*
|
311 ± 4*
|
318 ± 6*
|
|
CVVH
|
297 ± 15
|
312 ± 7*
|
316 ± 12*
|
315 ± 21*
|
326 ± 9*
#
|
332 ± 11*#
|
- Hemodynamic parameters were monintored in animals before and 15, 50, 120, 180, and 240 minutes after involuntary intratracheal sea water infusion. All animals received mechanical ventilation after sea water infusion and then were randomly divided into control and CVVH group *p < 0.05, vs, the same group of animals before infusion (baseline); #p < 0.05, vs, animals in control group at the same time point
