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Table 5 The ROC analysis results of the continuous variables

From: Validity of modified early warning, Glasgow Blatchford, and pre-endoscopic Rockall scores in predicting prognosis of patients presenting to emergency department with upper gastrointestinal bleeding

 

Cut off

AUC (p value)

Sensitivity [95 % CI]

Specifity [95 % CI]

PPV [95 % CI]

NPV [95 % CI]

LR+ [95 % CI]

LR- [95 % CI]

Bleeding at follow-up

GBS

>11

0.613 (0.0237)

70.59 [52.5–84.9]

51.19 [43.4–59.0]

22.64 [15.1–31.8]

89.58 [81.7–94.9]

1.45 [1.1–1.9]

0.57 [0.3–1.0]

MEWS

>4

0.500 (1.000)

14.71 [5.0–31.1]

94.05 [89.3–97.1]

33.33 [11.8–61.6]

84.49 [78.5–89.4]

2.47 [0.9–6.8]

0.91 [0.8–1.0]

PER

>4

0.600 (0.0550)

44.12 [27.2–61.1]

76.19 [69.0–82.4]

27.27 [16.1–41.0]

87.07 [80.6–92.0]

1.85 [1.2–3.0]

0.73 [0.5–1.0]

Endoscopic therapy

GBS

>5

0.514 (0.7501)

94.64 [85.1–98.9]

10.49 [6–16.7]

29.28 [22.8–36.5]

83.33 [58.6–96.4]

1.06 [1–1.1]

0.51 [0.2–1.7]

MEWS

>1

0.508 (0.8623)

33.93 [21.8–47.8]

71.33 [63.2–78.6]

31.67 [20.3–45.0]

73.38 [65.2–80.5]

1.18 [0.8–1.9]

0.93 [0.7–1.1]

PER

>3

0.577 (0.0769)

57.14 [43.2–70.3]

54.55 [46.0–62.9]

32.99 [23.8–43.3]

76.47 [67.0–84.3]

1.26 [0.9–1.7]

0.79 [0.6–1.1]

Need for blood transfusion

GBS

>10

0.829 (<0.0001)

79.45 [72.0–85.7]

76.79 [63.6–87.0]

89.92 [83.4–94.5]

58.90 [46.8–70.39

3.42 [2.1–5.6]

0.27 [0.2–0.4]

MEWS

>1

0.584 (0.0470)

73.29 [65.3–80.3]

39.29 [26.5–53.2]

75.89 [68.0–82.7]

36.07 [24.2–49.4]

1.21 [1.0–1.5]

0.68 [0.4–1.0]

PER

>3

0.642 (0.0014)

55.48 [47.0–63.7]

67.86 [54.0–79.7]

81.82 [72.8–88.9]

36.89 [27.6–47.0]

1.73 [1.1–2.6]

0.66 [0.5–0.8]

Death

GBS

>13

0.679 (0.0222)

63.64 [30.8–89.1]

72.77 [65.9–79.0]

11.86 [4.9–22.9]

97.20 [93.0–99.2]

2.34 [1.4–3.9]

0.50 [0.2–1.1]

MEWS

>2

0.772 (<0.0001)

72.73 [39.0–94.0]

65.45 [58.2–72.2]

10.81 [4.8–20.2]

97.66 [93.3–99.5]

2.10 [1.4–3.2]

0.42 [0.2–1.1]

PER

>3

0.767 (<0.0001)

90.91 [58.7–99.8]

53.40 [46.1–60.6]

10.10 [5.0–17.8]

99.03 [94.7–100.0]

1.95 [1.5–2.5]

0.17 [0.03–1.1]

Rebleeding

GBS

>12

0.663 (0.0073)

70.83 [48.9–87.4]

65.27 [57.5–72.5]

22.67 [13.8–33.8]

93.97 [88.0–97.5]

2.04 [1.5–2.8]

0.45 [0.2–0.8]

MEWS

>2

0.617 (0.0638)

50.0 [29.1–70.9]

67.66 [60.0–74.7]

18.18 [9.8–29.6]

90.40 [83.8–94.9]

1.55 [1.0–2.4]

0.74 [0.5–1.1]

PER

>3

0.832 (<0.0001)

95.83 [78.9–99.9]

60.48 [52.6–67.9]

25.84 [17.1–36.2]

99.02 [94.7–100.0]

2.42 [2.0–3.0]

0.07 [0.01–0.5]

  1. the “Bold numbers” p<0.05. Abbreviations: GBS Glasgow Blatchford score, MEWS Modified early warning score, PER pre-endoscopic rockall, ROC receiver operator characteristic, AUC receiver operating characteristic curve, PPV positive predictive value, NPV negative predictive value, LR likelihood ratio, CI confidence intervals