Table 9 Distribution of Haplotype frequency in non-survivors and survivors patients
Cytokine gene | Haplotypes | Distribution of haplotype in survivors and non-survivors patients | |||
|---|---|---|---|---|---|
Polymorphism | Survivors | Non-survivors | χ 2 | p value | |
n (%) | n (%) | ||||
TGF-β codon 10 C/T& codon25 G/C | CG | 65(84.4) | 26(70.2) | ||
CC | 0(0) | 3(8.1) | 7.3 | 0.02 | |
TG | 12(15.6) | 8(21.7) | |||
TNF-α-308 G/A &-238 G/A | GG | 75(97.4) | 34(91.9) | ||
GA | 1(1.3) | 1(2.7) | 1.9 | 0.22 | |
AG | 1(1.3) | 2(5.4) | |||
IL2 -330 T/G & + 160 G/T | GG | 18(23.3) | 6(16.2) | ||
TG | 55(71.4) | 19(78.4) | 3.2 | 0.37 | |
GT | 0(0) | 1(2.7) | |||
TT | 4(5.2) | 1(2.7) | |||
IL4-1098 T/G, −590 C/T & -590 C/T | GCC | 1(1.3) | 1(2.7) | ||
TCC | 64(83.1) | 26(70.3) | 2.5 | 0.25 | |
TTT | 12(15.6) | 10(27) | |||
IL6-174 G/C & + 565 A/G | GG | 74(96.1) | 36(97.3) | ||
CG | 1(1.3) | 0(0) | 0.48 | 0.99 | |
GA | 2(2.6) | 1(2.7) | |||
IL10 -1082 G/A, −819C/T &-592 C/A | GCC | 26(33.7) | 12(32.4) | ||
ACC | 47(61.1) | 24(64.8) | 0.42 | 0.99 | |
ATA | 4(5.2) | 1(2.8) | |||