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Table 8 Distribution of genotypes in non-survivors and survivors patients using multivariate logistic regression analysis

From: Clinical relevance of single nucleotide polymorphisms within the 13 cytokine genes in North Indian trauma hemorrhagic shock patients

Name of the cytokine gene with position Genotype Survivors Non-survivors Unadjusted odds ratio Adjusted odds ratio
f (%) f (%) OR (95 % CI) p value OR (95 % CI) p value
n = 77 n = 37
IL-1R(pst I 1970) CC 29(37.6) 9(24.3) 1   1  
CT 41(53.2) 17(45.9) 1.3(0.52–3.4) 0.54 0.9(0.06–14.8) 0.99
TT 7(9.0) 11(29.8) 5.0(1.5–16.9) 0.08 19.9(0.6–577) 0.08
IL4R(+1902) AA 51(66.2) 17(46) 1   1  
GA 22(28.6) 16(43) 2.1(0.93–5.0) 0.07 3.6(1.0–12.4) 0.48
GG 4(5.2) 4(11) 3(0.67–13.3) 0.14 21.8(3.2–148) 0.61
IL-1β(−511) CC 34(44.1) 9(24.4) 1   1  
CT 27(35) 20(54) 2.7(1.0–7.1) 0.03 9.8(0.75–128.2) 0.08
TT 16(20.9) 8(21.6) 1.8(0.61–5.8) 0.26 3.2(0.09–114 0.51
TGF-β(codon25) CC 61(79.2) 26(70.27) 1   1  
CG 14(18.2) 8(21.62) 1.3(0.50–3.6) 0.55 1.7(0.50–6.4) 0.37
GG 2(2.6) 3(8.1) 3.5(0.55–22.3) 0.18 15(1.5–141) 0.01
  1. Adjusted odds ratio at 95 % CI of genotypes with ISS and SOFA score