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Table 7 Comparison of genotypic and allelic frequency in non-survivors and survivors patients

From: Clinical relevance of single nucleotide polymorphisms within the 13 cytokine genes in North Indian trauma hemorrhagic shock patients

Cytokine gene polymorphism Genotype/Allele Survivors Non-survivors p Value OR (95 % CI)
n (%) n (%)
n = 77 n = 37
IL-1β(−511) CC 34(44.1) 9(24.4)   1
CT 27(35) 20(54) 0.03 2.7(1.0–7.1)
TT 16(20.9) 8(21.6)   1.8(0.61–5.8)
C 95(83.3) 38(51.3) 0.13 1
T 59(16.7) 36(49.7)   1.5(0.83–2.7)
IL-1R(pst I 1970) CC 29(37.6) 9(24.3)   1
CT 41(53.2) 17(45.9) 0.02 1.3(0.52–3.4)
TT 7(9.0) 11(29.8)   5.0(1.5–16.9)
C 99(64.2) 35(47.3) 0.01 1
T 55(35.8) 39(52.7)   2.0(1.0–3.6)
IL-4R(+1902) AA 51(66.2) 17(46)   1
GA 22(28.6) 16(43) 0.08 2.1(0.93–5.0)
GG 4(5.2) 4(11)   3(0.67–13.3)
A 124(80.5) 15(20.2) 0.001 1
G 30(19.5) 59(79.8)   16.2(7.7–34.7)
IL-12(−1188) CC 10(12.9) 3(8.1)   1
CA 25(32.4) 9(24.3) 0.49 1.2(0.26–5.3)
AA 42(54.7) 25(67.6)   1.9(0.49–7.9)
C 45(29.2) 47(20.2) 0.001 1
A 109(70.8) 27(79.8)   0.23(0.12–0.44)
TGF-β(codon25) CC 61(79.2) 26(70.27)   1
CG 14(18.2) 8(21.62) 0.04 1.3(0.50–3.6)
GG 2(2.6) 3(8.1)   3.5(0.55–22.3)
C 136(88.3) 60(81.1) 0.14 1
G 18(11.7) 14(18.9)   0.56(0.24–1.3)