Table 6 Distribution of haplotype in patient with sepsis and non-sepsis
Cytokine gene | Haplotypes | Distribution of haplotype in patients with sepsis and non-sepsis | |||
|---|---|---|---|---|---|
Polymorphism | Sepsis patients | Non-sepsis patients | χ 2 | p value | |
n (%) | n (%) | ||||
TGF-β codon 10 C/T& codon25 G/C | CG | 19(76) | 72(80.9) | ||
CC | 2(8) | 1(1.1) | 3.6 | 0.18 | |
TG | 4(16) | 16(18.0) | |||
TNF-α-308 G/A &-238 G/A | GG | 21(92) | 86(96.7) | ||
GA | 2(8) | 0(0) | 8.0 | 0.05 | |
AG | 0(0) | 3(3.3) | |||
IL2 -330 T/G & + 160 G/T | GG | 6(24) | 18(20.2) | ||
TG | 19(76) | 65(73) | 1.8 | 0.76 | |
GT | 0(0) | 1(1.1) | |||
TT | 0(0) | 5(5.7) | |||
IL4-1098 T/G, −590 C/T & -590 C/T | GCC | 0(0) | 2(2.2) | ||
TCC | 20(80) | 70(78.6) | 0.57 | 0.99 | |
TTT | 5(20) | 17(19.2) | |||
IL6-174 G/C & + 565 A/G | GG | 24(96) | 86(96.6) | 0.50 | 0.63 |
CG | 0(0) | 1(1.1) | |||
GA | 1(4) | 2(2.3) | |||
IL10 -1082 G/A, −819C/T &-592 C/A | GCC | 8(32) | 30(33.7) | ||
ACC | 13(52) | 58(65.1) | 10.4 | 0.01 | |
ATA | 4(16) | 1(1.2) | |||