EF24 treatment reduces hemorrhage-induced CINC-1 and HMGB1 expression. (A) CINC expression in liver tissue estimated by ELISA (n = 4/group). (B) HMGB1 expression in liver tissue of hemorrhaged rats treated with EF24 (n = 4/group). The protein expression of HMGB1 was observed by immunoblotting (Upper panel), and the actin-normalized densitometry units were calculated (Lower panel). * p < 0.05 vs. Ctrl and # p < 0.05 vs. HS.