From: Transfusion therapy in paediatric trauma patients: a review of the literature
Author | No. | Type of study | FFP:RBC ratio high vs. low | PLT:RBC ratio high vs. low | Mortality high vs. low | Comments |
---|---|---|---|---|---|---|
Hendrickson et al. [3] | 102 | RC vs. PI | 1:1.8 vs. 1:3.6 | 1:6.7 vs. 1:5.9 | 38% vs. 23% (p=0.35) | The majority of pre-MTP (80%) and MTP (72%) patients had at least one abnormal coagulation value on presentation to the ED1 |
Chidester et al. [20] | 55 | PI | 1:3 vs. 1:3 | NR | 45% vs. 45% (p value NR) | Early coagulopathy2 initiated MTP. 4 thrombo-embolic events in the non-MTP group vs. 0 in the MTP group |
Dressler et al. [56] | 1 | Case | 4:4 | 5:4 | NA | Â |
Pickett et al. [57] | 1 | Case | 3:6 | 5:6 | NA | Â |
Paterson et al. [58] | 1 | Case | 1:1.5 | 1:1.5 | NA | Â |