From: Functional capacity of reconstituted blood in 1:1:1 versus 3:1:1 ratios: A thrombelastometry study
Parameter | 1:1:1 | 3:1:1 | ||||||
---|---|---|---|---|---|---|---|---|
Day 1 | Day 4 | Day 14 | Day 24 | Day 1 | Day 4 | Day 14 | Day 24 | |
Leukocytes [×103/μl] | 0.25 ± 0.05c | 0.37 ± 0.08 | 0.35 ± 0.1 | 0.45 ± 0.1 | 0.33 ± 0.1 | 0.33 ± 0.14 | 0.25 ± 0.08 | 0.5 ± 0.18 |
pH | 7.04 ± 0.04b,c | 7.03 ± 0.05e | 6.91 ± 0.08 | 6.89 ± 0.03 | 6.95 ± 0.05b,c | 6.9 ± 0.04e | 6.76 ± 0.03 | 6.69 ± 0.06 |
Sodium [mM] | 142.62 ± 6.15c | 140.48 ± 1.63e | 138.67 ± 0.81 | 137.42 ± 0.99 | 145.37 ± 5.14b,c | 142.3 ± 0.89e | 138.43 ± 2.09 | 136.72 ± 1.67 |
Potassium [mM] | 3.12 ± 0.38b,c | 3.91 ± 0.38e | 6.72 ± 1.3 | 7.45 ± 0.48 | 2.83 ± 0.78b,c | 4.69 ± 0.35e | 9.19 ± 0.95 | 13.01 ± 0.15 |
INTEM CT [s] | 204.83 ± 13.6c | 229.33 ± 28.51 | 243.5 ± 121.51 | 284.33 ± 67.57 | 206.83 ± 16.46 | 200.83 ± 14.93e | 245 ± 84.52 | 259.83 ± 25.86 |
FIBTEM CT [s] | 57.83 ± 10.65 | 108.33 ± 91.24 | 69.5 ± 38.9 | 46.17 ± 29.17 | 84.33 ± 15.72c | 52.33 ± 26.24 | 132.33 ± 107.69 | 45.17 ± 19.09 |
INR | 1.03 ± 0.05c | 1.13 ± 0.05 | 1.12 ± 0.04 | 1.17 ± 0.08 | 1.23 ± 0.08 b | 1.52 ± 0.25 | 1.53 ± 0.15 | 1.45 ± 0.14 |
Factor II [%] | 76.33 ± 4.23c | 74 ± 5.48 | 68.5 ± 8.07 | 63.17 ± 5.34 | 55.17 ± 7.19 | 46.33 ± 8.71 | 43.83 ± 9.7 | 45.67 ± 5.54 |
Factor V [%] | 72.67 ± 6.89a,c | 57.33 ± 4.41 | 58.67 ± 3.72 | 56.33 ± 6.98 | 53 ± 10.1a,b | 34.5 ± 6.25 | 35.83 ± 2.64 | 40.33 ± 5.09 |
Factor VII [%] | 79.83 ± 10.46c | 67.17 ± 9.15 | 64.67 ± 9.67 | 61.17 ± 11.41 | 56.33 ± 7.76 | 42 ± 9.27 | 41.33 ± 8.31 | 45 ± 9.92 |
Factor IX [%] | 95 ± 5.22b | 87 ± 5.33 | 74.5 ± 10.91 | 77.3 ± 16.37 | 70.67 ± 8.62c | 54.5 ± 10.56 | 51.17 ± 11.36 | 50.67 ± 9.14 |
Factor XI [%] | 96 ± 15.3 | 91.83 ± 18.8 | 72.67 ± 15.07 | 66.5 ± 11.78 | 71.67 ± 6.35b,c | 72.83 ± 33.88 | 49.5 ± 12.32 | 48.17 ± 8.33 |
Factor XIII [%] | 100.67 ± 12.4 | 97.5 ± 11.71 | 86.33 ± 6.38 | 92.17 ± 19.05 | 77.17 ± 10.67c | 67.17 ± 16.04 | 65.5 ± 4.09 | 61 ± 1.79 |
Protein C activity [%] | 70.33 ± 5.96 | 70.67 ± 7.42 | 60.67 ± 6.74 | 63.67 ± 5.16 | 50.5 ± 4.97b | 41.33 ± 8.36 | 37.33 ± 7.26 | 48.17 ± 6.97 |
Protein S activity [%] | 60.33 ± 7.12b | 33 ± 4.34 | 55 ± 8.12 | 43.83 ± 15.42 | 43.17 ± 11.41a | 21.17 ± 8.82 | 33.33 ± 7.39 | 28.83 ± 12.24 |
D-dimer [μg/l] | 216.6 ± 48.43b | 239.5 ± 43.98d | 123 ± 26.78 | 156 ± 50.45 | 185.2 ± 36.64 | 180.67 ± 37.6 | 119.5 ± 17.04 | 150.5 ± 32.44 |