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Table 4 Performance measures of the prognostic models on the INRO-PH validation dataset

From: Performance of IMPACT, CRASH and Nijmegen models in predicting six month outcome of patients with severe or moderate TBI: an external validation study

Performance measures (prediction of six-month unfavourable outcome) AUCVAL(CI 95%) AUCREFIT Slope Intercept P- value*
IMPACT Core Model 0.8 (0.76-0.84) 0.82 1.073 -0.354 0.93
IMPACT Extended Model 0.81 (0.77-0.86) 0.87 1.061 -0.506 0.65
CRASH Basic Model 0.8 (0.75-0.84) 0.82 0.871 -0.505 Reference
Nijmegen Demographic and Clinical Model 0.82 (0.77-0.87) 0.83 0.865 -0.738 0.47
Performance measures (prediction of six-month mortality) AUC VAL AUC REFIT Slope Intercept P- value*
IMPACT Core Model 0.84 (0.8-0.87) 0.86 1.381 -0.211 0.55
IMPACT Extended Model 0.85 (0.81-0.89) 0.9 1.323 -0.243 0.32
CRASH Basic Model 0.82 (0.77-0.87) 0.85 0.866 0.207 Reference
Nijmegen Demographic and Clinical Model 0.86 (0.82-0.91) 0.87 0.984 -0.289 0.19
  1. AUC VAL = Area under the curve of external validation; AUC REFIT = Area under the curve of the refitted models; CI = Confidence Interval.
  2. *P value refers to difference between AUC VAL: The model with the lowest AUCVAL was taken as a reference and tested with all other AUCVAL.