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Table 4 Performance measures of the prognostic models on the INRO-PH validation dataset

From: Performance of IMPACT, CRASH and Nijmegen models in predicting six month outcome of patients with severe or moderate TBI: an external validation study

Performance measures (prediction of six-month unfavourable outcome)

AUCVAL(CI 95%)

AUCREFIT

Slope

Intercept

P- value*

IMPACT Core Model

0.8 (0.76-0.84)

0.82

1.073

-0.354

0.93

IMPACT Extended Model

0.81 (0.77-0.86)

0.87

1.061

-0.506

0.65

CRASH Basic Model

0.8 (0.75-0.84)

0.82

0.871

-0.505

Reference

Nijmegen Demographic and Clinical Model

0.82 (0.77-0.87)

0.83

0.865

-0.738

0.47

Performance measures (prediction of six-month mortality)

AUC VAL

AUC REFIT

Slope

Intercept

P- value*

IMPACT Core Model

0.84 (0.8-0.87)

0.86

1.381

-0.211

0.55

IMPACT Extended Model

0.85 (0.81-0.89)

0.9

1.323

-0.243

0.32

CRASH Basic Model

0.82 (0.77-0.87)

0.85

0.866

0.207

Reference

Nijmegen Demographic and Clinical Model

0.86 (0.82-0.91)

0.87

0.984

-0.289

0.19

  1. AUC VAL = Area under the curve of external validation; AUC REFIT = Area under the curve of the refitted models; CI = Confidence Interval.
  2. *P value refers to difference between AUC VAL: The model with the lowest AUCVAL was taken as a reference and tested with all other AUCVAL.