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Table 3 Laboratory data associated with gas exchange and coagulation

From: Venovenous extracorporeal life support for posttraumatic respiratory distress syndrome in adults: the risk of major hemorrhages

Variable

Survivors (n = 14)

Non-survivors (n = 6)

p

Patient with hemorrhagic complication (n = 7)

Patient without hemorrhage complications (n = 13)

p

Pre-ECLS data

PaO2 (mmHg)

56 (48–73)

55 (42–67)

0.55

53 (42–66)

58 (49–69)

0.59

PaO2/FiO2 ratio (mmHg)

56 (48–73)

57 (42–68)

0.66

53 (42–66)

58 (49–70)

0.7

PaCO2 (mmHg)

61 (47–89)

52 (41–76)

0.64

49 (40–78)

52 (49–91)

1.0

Hemoglobin (g/dL)

11 (10–13)

9 (8–11)

0.06

10 (9–15)

11 (9–12)

0.64

Platelet count (×109/L)

164 (90–193)

88 (51–34)

0.11

172 (107–183)

115 (67–193)

0.76

INR of Prothrombin Time > 1.2

7

6

0.05*

5

8

1.0

aPTT > 35 (seconds)

7

3

1.0

5

5

0.35

Data collected on ECLS at1 hour

PaO2/FiO2 ratio (mmHg)

108 (65–103)

103 (71–151)

0.84

99 (166–146)

110 (74–171)

0.54

PaCO2 (mmHg)

37 (30–46)

39 (31–45)

0.46

42 (35–44)

35 (27–48)

1.0

Hemoglobin g/dL)

10 (9–11)

10 (9–14)

0.72

10 (8–12)

10 (9–11)

0.76

Platelet count (×109/L)

98 (65–153)

100 (45–134)

0.72

99 (31–142)

100 (64–160)

0.54

INR of Prothrombin Time > 12

2

1

1.0

3

0

0.03*

aPTT > 120 (seconds)

10

6

0.27

6

10

1.0

at24 hour

PaO2/FiO2 ratio (mmHg)

190 (100–246)

93 (86–262)

0.44

98 (86–238)

180 (96–252)

0.59

Hemoglobin (g/dL)

10 (9–11)

10 (9–12)

0.6

10 (8.8-12)

10 (9–11)

0.82

Platelet count (×109/L)

99 (63–139)

76 (62–92)

0.18

75 (62–93)

96 (73–131)

0.18

Before ECLS weaning

      

PaO2/FiO2 ratio (mmHg)

261 (186–338)

-

-

229 (135–256)

288 (178–343)

0.18

  1. Numerical variable is presented as median and interquartile range (IQR).
  2. ECLS: Extracorporeal life support. PaO 2 /FiO 2 ratio: The arterial oxygen tension (PaO 2 ) divided by the fraction of inspired oxygen (FiO 2 ). INR: International normalized ratio. aPTT: Activated partial thromboplastin time. TIC: Trauma induced coagulopathy (INR > 1.3 or aPTT > > 35). *p < 0.05. The maximum of the detectable values.