Skip to main content

Table 2 Comparison of serum solute concentrations between control and hemofiltration-treated dogs with heat stroke

From: Clearance of serum solutes by hemofiltration in dogs with severe heat stroke

Solute Group Baseline Heat stroke 0 h Time after hemofiltration
1 h 2 h 3 h
TNF-α, ng/L C 14.9 ± 2.6 93.6 ± 19.7 150.6 ± 20 219.2 ± 31.7†‡ 226.1 ± 27†‡
HF 15.2 ± 2.6 94 ± 23.6 99.2 ± 19.6* 102.4 ± 22.7* 96.7 ± 19.9*
IL-6, ng/L C 56.1 ± 7.4 128.5 ± 20.2 149.9 ± 13.4 167.4 ± 17.1 173 ± 15.5
HF 56 ± 7.7 126.1 ± 15.6 122.6 ± 15.3 119.1 ± 17.3* 118.5 ± 19.2*
IL-10, ng/L C 20.3 ± 2.8 65.8 ± 10.2 132.9 ± 13.6 158.2 ± 12.5†‡ 164.7 ± 12†‡
HF 21 ± 3.6 63.2 ± 11.2 69.2 ± 8.4* 70.8 ± 8* 68.8 ± 7.7*
BUN, mmol/L C 4.29 ± 0.82 10.5 ± 1.6 11.9 ± 1.3 12.6 ± 1.2 14.2 ± 1.3
HF 4.2 ± 0.9 10.6 ± 2.4 6.3 ± 1.4* 5.0 ± 1.3* 4.0 ± 0.9*
Creatinine, μmol/L C 59.9 ± 12.7 118.5 ± 21.3 156 ± 26.2 179.3 ± 22.5 194.3 ± 21
HF 59.5 ± 12.2 122 ± 23.8 88.9 ± 29.5* 65.6 ± 20.4* 54.9 ± 16.5*
  1. Data are presented as mean ± standard deviation. BUN, blood urea nitrogen; C, control; HF, hemofiltration; IL, interleukin; TNF, tumor necrosis factor.
  2. *P < 0.05 significantly different between C and HF groups for given time points.
  3. P < 0.01 (0.05/5) compared with the 0 h time point in the same group, after Bonferroni correction.
  4. P < 0.01 (0.05/5) compared with the 1 h time point in the same group, after Bonferroni correction.