Skip to main content

Table 2 Comparison of serum solute concentrations between control and hemofiltration-treated dogs with heat stroke

From: Clearance of serum solutes by hemofiltration in dogs with severe heat stroke

Solute

Group

Baseline

Heat stroke 0 h

Time after hemofiltration

1 h

2 h

3 h

TNF-α, ng/L

C

14.9 ± 2.6

93.6 ± 19.7

150.6 ± 20

219.2 ± 31.7†‡

226.1 ± 27†‡

HF

15.2 ± 2.6

94 ± 23.6

99.2 ± 19.6*

102.4 ± 22.7*

96.7 ± 19.9*

IL-6, ng/L

C

56.1 ± 7.4

128.5 ± 20.2

149.9 ± 13.4

167.4 ± 17.1

173 ± 15.5

HF

56 ± 7.7

126.1 ± 15.6

122.6 ± 15.3

119.1 ± 17.3*

118.5 ± 19.2*

IL-10, ng/L

C

20.3 ± 2.8

65.8 ± 10.2

132.9 ± 13.6

158.2 ± 12.5†‡

164.7 ± 12†‡

HF

21 ± 3.6

63.2 ± 11.2

69.2 ± 8.4*

70.8 ± 8*

68.8 ± 7.7*

BUN, mmol/L

C

4.29 ± 0.82

10.5 ± 1.6

11.9 ± 1.3

12.6 ± 1.2

14.2 ± 1.3

HF

4.2 ± 0.9

10.6 ± 2.4

6.3 ± 1.4*

5.0 ± 1.3*

4.0 ± 0.9*

Creatinine, μmol/L

C

59.9 ± 12.7

118.5 ± 21.3

156 ± 26.2

179.3 ± 22.5

194.3 ± 21

HF

59.5 ± 12.2

122 ± 23.8

88.9 ± 29.5*

65.6 ± 20.4*

54.9 ± 16.5*

  1. Data are presented as mean ± standard deviation. BUN, blood urea nitrogen; C, control; HF, hemofiltration; IL, interleukin; TNF, tumor necrosis factor.
  2. *P < 0.05 significantly different between C and HF groups for given time points.
  3. P < 0.01 (0.05/5) compared with the 0 h time point in the same group, after Bonferroni correction.
  4. P < 0.01 (0.05/5) compared with the 1 h time point in the same group, after Bonferroni correction.