Clearance rates after hemofiltration in dogs with heat stroke for (A) TNF-α, (B) IL-6, (C) BUN, and (D) creatinine. Data are presented as mean ± standard deviation and compared using ANOVA test with Bonferroni correction for post-hoc comparisons. *P < 0.0167 (0.05/3) compared with the 1 h time point, after Bonferroni correction. IL-10 is not shown because it was not detected. Abbreviations: BUN, blood urea nitrogen; C, control; HF, hemofiltration; IL, interleukin; TNF, tumor necrosis factor.