| |
Non-bacteremic Patients *n (%)
|
Bacteremic Patients n (%)
|
Sensitivity (95% CI)
|
Specificity (95% CI)
|
PPV (95% CI)
|
NPV (95% CI)
|
+ LR (95% CI)
|
- LR (95% CI)
|
|---|
|
Temperature > 38.0°C
|
1879 (88.5)
|
245 (11.5)
|
64.3 (59.3–69.1)
|
80.8 (80.0–81.6)
|
11.5 (10.2–13.0)
|
98.3 (98.0–98.6)
|
3.4 (3.1–3.6)
|
0.4 (0.4–0.5)
|
|
CRP ≥ 100 mg/dL
|
2064 (88.2)
|
277 (11.8)
|
67.4 (62.6–71.9)
|
79.0 (78.2–79.8)
|
11.8 (10.6–13.2)
|
98.3 (98.0–98.6)
|
3.2 (3.0–3.5)
|
0.4 (0.3–0.5)
|
|
SIRS
|
3546 (92.2)
|
301 (7.8)
|
72.0 (67.4–76.3)
|
69.4 (68.5–70.2)
|
7.8 (6.9–8.7)
|
98.6 (98.3–98.8)
|
2.4 (2.2–2.5)
|
0.4 (0.3–0.5)
|
|
Combination test
|
7140 (94.7)
|
397 (5.3)
|
95.0 (92.4–96.9)
|
38.3 (37.4–39.2)
|
5.3 (4.8–5.8)
|
99.5 (99.3–99-7)
|
1.5 (1.5–1.6)
|
0.1 (0.1–0.2)
|
- Results of the diagnostic tests for the clinical parameters temperature, C-reactive protein (CRP), the Systemic Inflammatory Response Syndrome (SIRS) and the Combination test (Temperature >38°C, or a CRP > 100 mg/dL or ≥2 SIRS criteria). Analysed in all adult Medical Emergency Department patients (n = 11,988). PPV: Positive Predictive Value. NPV: Negative Predictive Value. +LR: Positive Likelihood Ratio, −LR: Negative Likelihood Ratio. CI: 95% Confidence Interval.
- *: Non blood-cultured and blood cultured non-bacteraemic patients. The percent is presented horizontally.
