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Table 2 Clinical characteristics dependent on RBC transfusion on consecutive days of septic shock

From: Red blood cell transfusion in septic shock - clinical characteristics and outcome of unselected patients in a prospective, multicentre cohort

Day 1 RBC No RBC P value
Number of patients (%) 34 (16) 179 (84) -
Bleeding episode, n (%) 7 (21) 0 < 0.0001
SOFA 12 (9-14) 9 (7-12) 0.0004
NA dose (max) (μg/kg/min) 0.20 (0.07-0.35) 0.15 (0.06-0.30) 0.27
Haemoglobin (min) (g/dl) 7.3 (6.8-7.9) 10.0 (8.9-11.1) < 0.0001
ScvO2 (min) (%) 68 (51-76), n = 16 71 (65-76), n = 83 0.21
Lactate (max) (mmol/l) 3.1 (1.5-7.9) 2.8 (1.7-4.6), n = 178 0.39
Day 2    
Number of patients (%) 32 (17) 156 (83) -
Bleeding episode, n (%) 8 (25) 0 < 0.0001
SOFA 9 (8-13) 9 (7-13) 0.91
NA dose (max) (μg/kg/min) 0.13 (0.08-0.22) 0.15 (0.07-030) 0.49
Haemoglobin (min) (g/dl) 7.9 (7.6-8.7) 9.7 (8.9-10.5) < 0.0001
ScvO2 (min), (%) 71 (68-75), n = 21 72 (65-76), n = 68 0.85
Lactate (max) (mmol/l) 2.0 (1.3-4.1) 2.3 (1.6-3.3), n = 155 0.72
Day 3    
Number of patients (%) 31 (24) 98 (76) -
Bleeding episode, n (%) 4 (13) 0 0.0003
SOFA 10 (9-14) 10 (7-12) 0.21
NA dose (max) (μg/kg/min) 0.16 (0.09-0.25) 0.13 (0.08-0.26) 0.39
Haemoglobin (min) (g/dl) 8.2 (7.4-8.5) 9.7 (9.0-10.3) < 0.0001
ScvO2 (min) (%) 67 (63-72), n = 18 72 (64-75), n = 38 0.15
Lactate (max) (mmol/l) 2.0 (1.5-3.0) 1.9 (1.4-2.6), n = 97 0.45
Day 4    
Number of patients (%) 17 (17) 82 (83) -
Bleeding episode, n (%) 3 (18) 0 0.0001
SOFA 12 (9-14) 10 (8-14) 0.34
NA dose (max) (μg/kg/min) 0.13 (6-25) 0.10 (6-19) 0.43
Haemoglobin (min) (g/dl) 8.4 (7.9-8.7) 9.3 (8.5-10.0) 0.0004
ScvO2 (min) (%) 70 (65-72), n = 10 66 (63-76), n = 20 0.80
Lactate (max) (mmol/l) 1.7 (1.2-2.4) 1.7 (1.3-2.7), n = 81 0.60
Day 5    
Number of patients (%) 18 (24) 58 (76) -
Bleeding episode, n (%) 4 (22) 0 0.0002
SOFA 14 (12-16) 10 (8-13) 0.01
NA dose (max) (μg/kg/min) 0.14 (0.08-0.40) 0.12 (0.04-0.20) 0.08
Haemoglobin (min) (g/dl) 7.7 (7.1-8.5) 9.5 (8.7-10.3) < 0.0001
ScvO2 (min) (%) 74 (69-78), n = 6 67 (63-77), n = 19 0.30
Lactate (max) (mmol/l) 2.3 (1.5-3.3) 1.7 (1.4-2.3) 0.33
  1. Values are as medians (interquartile ranges) of those patients with registered data; n is given in the cells, if not all patients had the value registered.
  2. Min, minimum; max, maximum; n, number; NA, noradrenalin; SOFA, sequential organ failure assessment; ScvO2, central venous oxygen saturation.