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Table 2 Clinical characteristics dependent on RBC transfusion on consecutive days of septic shock

From: Red blood cell transfusion in septic shock - clinical characteristics and outcome of unselected patients in a prospective, multicentre cohort

Day 1

RBC

No RBC

P value

Number of patients (%)

34 (16)

179 (84)

-

Bleeding episode, n (%)

7 (21)

0

< 0.0001

SOFA

12 (9-14)

9 (7-12)

0.0004

NA dose (max) (μg/kg/min)

0.20 (0.07-0.35)

0.15 (0.06-0.30)

0.27

Haemoglobin (min) (g/dl)

7.3 (6.8-7.9)

10.0 (8.9-11.1)

< 0.0001

ScvO2 (min) (%)

68 (51-76), n = 16

71 (65-76), n = 83

0.21

Lactate (max) (mmol/l)

3.1 (1.5-7.9)

2.8 (1.7-4.6), n = 178

0.39

Day 2

   

Number of patients (%)

32 (17)

156 (83)

-

Bleeding episode, n (%)

8 (25)

0

< 0.0001

SOFA

9 (8-13)

9 (7-13)

0.91

NA dose (max) (μg/kg/min)

0.13 (0.08-0.22)

0.15 (0.07-030)

0.49

Haemoglobin (min) (g/dl)

7.9 (7.6-8.7)

9.7 (8.9-10.5)

< 0.0001

ScvO2 (min), (%)

71 (68-75), n = 21

72 (65-76), n = 68

0.85

Lactate (max) (mmol/l)

2.0 (1.3-4.1)

2.3 (1.6-3.3), n = 155

0.72

Day 3

   

Number of patients (%)

31 (24)

98 (76)

-

Bleeding episode, n (%)

4 (13)

0

0.0003

SOFA

10 (9-14)

10 (7-12)

0.21

NA dose (max) (μg/kg/min)

0.16 (0.09-0.25)

0.13 (0.08-0.26)

0.39

Haemoglobin (min) (g/dl)

8.2 (7.4-8.5)

9.7 (9.0-10.3)

< 0.0001

ScvO2 (min) (%)

67 (63-72), n = 18

72 (64-75), n = 38

0.15

Lactate (max) (mmol/l)

2.0 (1.5-3.0)

1.9 (1.4-2.6), n = 97

0.45

Day 4

   

Number of patients (%)

17 (17)

82 (83)

-

Bleeding episode, n (%)

3 (18)

0

0.0001

SOFA

12 (9-14)

10 (8-14)

0.34

NA dose (max) (μg/kg/min)

0.13 (6-25)

0.10 (6-19)

0.43

Haemoglobin (min) (g/dl)

8.4 (7.9-8.7)

9.3 (8.5-10.0)

0.0004

ScvO2 (min) (%)

70 (65-72), n = 10

66 (63-76), n = 20

0.80

Lactate (max) (mmol/l)

1.7 (1.2-2.4)

1.7 (1.3-2.7), n = 81

0.60

Day 5

   

Number of patients (%)

18 (24)

58 (76)

-

Bleeding episode, n (%)

4 (22)

0

0.0002

SOFA

14 (12-16)

10 (8-13)

0.01

NA dose (max) (μg/kg/min)

0.14 (0.08-0.40)

0.12 (0.04-0.20)

0.08

Haemoglobin (min) (g/dl)

7.7 (7.1-8.5)

9.5 (8.7-10.3)

< 0.0001

ScvO2 (min) (%)

74 (69-78), n = 6

67 (63-77), n = 19

0.30

Lactate (max) (mmol/l)

2.3 (1.5-3.3)

1.7 (1.4-2.3)

0.33

  1. Values are as medians (interquartile ranges) of those patients with registered data; n is given in the cells, if not all patients had the value registered.
  2. Min, minimum; max, maximum; n, number; NA, noradrenalin; SOFA, sequential organ failure assessment; ScvO2, central venous oxygen saturation.