| |
Baseline
|
Resuscitation
|
3 h
|
6 h
|
|---|
|
Cardiac output (L/min)
|
|
Control
|
3.9 ± 0.3
|
4.3 ± 0.3
|
4.4 ± 0.4
|
3.6 ± 0.2
|
|
LR
|
3.7 ± 0.2
|
3.9 ± 0.3
|
3.5 ± 0.2
|
3.3 ± 0.2
|
|
NS
|
3.8 ± 0.3
|
5.9 ± 0.5*§♣
|
4.7 ± 0.3§
|
4.5 ± 0.2§♣
|
|
Stroke volume (ml/beat)
|
|
Control
|
36.5 ± 3.5
|
36.8 ± 2.2
|
36.8 ± 3.7
|
35.5 ± 3.9
|
|
LR
|
41.4 ± 3.3
|
24.9 ± 1.6*§♣
|
21.4 ± 2.3*§
|
24.7 ± 2.1*§
|
|
NS
|
38.2 ± 4.9
|
45.7 ± 4.7
|
38.1 ± 3.3
|
40.1 ± 3.3
|
|
Total Peripheral resistance (mm Hg/(L/min))
|
|
Control
|
20.4 ± 1.4
|
18.6 ± 2.0
|
17.3 ± 2.6
|
17.7 ± 1.3
|
|
LR
|
22.9 ± 1.0
|
17.7 ± 0.9*
|
17.9 ± 1.3*
|
17.4 ± 0.7*
|
|
NS
|
23.1 ± 1.8
|
12.5 ± 1.4*§
|
12.5 ± 0.7*§
|
12.0 ± 0.4*§
|
|
Hct (%)
|
|
Control
|
29.0 ± 0.8%
|
28.9 ± 0.9%
|
28.0 ± 0.9%
|
27.6 ± 1.0%
|
|
LR
|
30.2 ± 1.0%
|
13.1 ± 0.9%*♣
|
14.0 ± 0.7%*♣
|
14.7 ± 0.6%*♣
|
|
NS
|
29.0 ± 1.0%
|
11.6 ± 0.8 %*♣
|
12.5 ± 0.6%*♣
|
12.2 ± 0.7%*♣
|
- Animal groups include control (C, n = 6), hemorrhage with LR resuscitation (LR, n = 6), and hemorrhage with normal saline resuscitation (NS, n = 6). Data are expressed as means ± SE.
- *p < 0.05 compared to corresponding baseline values within the group; §p < 0.05 LR vs NS groups; and ♣p < 0.05 compared to corresponding control values.
