Table 1 Clinical data upon emergency room (ER) admission of patients receiving fibrinogen concentrate (FC)
FC group (n = 85) | FC–PCC group (n = 63) | FC–PCC–FFP group (n = 9) | p-value | |
|---|---|---|---|---|
Age (years) | 40 (27–58) | 45 (26–57) | 49 (29–58) | 0.99 |
Age >55 years, n (%) | 24 (28%) | 17 (27%) | 2 (22%) | 0.93 |
Male, n (%) | 73 (86%) | 51 (81%) | 6 (67%) | 0.31 |
Systolic BP (mmHg) | 110 (90–131) | 88 (75–125) | 83 (75–105) | 0.0068 |
Systolic BP ≤90 mmHg , n (%) | 23 (27%) | 32 (31%) | 5 (56%) | 0.0073 |
Temperature (°C) | 35.2 (34.1–36.0) | 35.7 (34.0–36.35) | 35.9 (35.2–36.4) | 0.39 |
ISS | 27 (20–34) | 34 (26–43) | 50 (42–58) | <0.0001 |
NISS | 30 (26–41) | 38 (28–50) | 50 (43–58) | 0.0002 |
ISS ≥16, n (%) | 76 (89%) | 63 (100%) | 9 (100%) | 0.018 |
ISS ≥25, n (%) | 53 (62%) | 48 (76%) | 9 (100%) | 0.025 |
GCS | 12 (5–15) | 10 (5–15) | 7 (4–15) | 0.58 |
pH | 7.33 (7.28–7.38) | 7.28 (7.22–7.35) | 7.26 (7.17–7.35) | 0.0025 |
BD (mmol/L) | 3.7 (1.9–5.8) | 5.6 (3.4–8.5) | 5.8 (4.1–10.7) | 0.0005 |
Lactate (mmol/L) | 2.12 (1.56–3.48) | 3.10 (2.27–5.45) | 7.51 (4.51–8.78) | 0.0001 |
Acute operative intervention*, n (%) | 74 (87%) | 57 (91%) | 9 (100%) | 0.45 |