EXTEM test results. Results from the extrinsically activated EXTEM assay, performed using ROTEM. Results were obtained at the following timepoints: upon emergency room (ER) admission, intensive care unit (ICU) admission and 24 hours after ER admission. Data are presented as median values; error bars represent interquartile ranges. CT, clotting time; CFT, clot formation time; MCF, maximum clot firmness. FC group, patients receiving fibrinogen concentrate only; FC–PCC group, patients receiving fibrinogen concentrate and prothrombin complex concentrate; FC–PCC–FFP group, patients receiving fibrinogen concentrate, prothrombin complex concentrate and fresh frozen plasma. *p < 0.05, ***p < 0.001, ns = not significant (unpaired t-test or Mann–Whitney U test).