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Table 1 Patients stratified by presence of coagulopathy

From: Time course of soluble P-selectin and von Willebrand factor levels in trauma patients: a prospective observational study

  Total Coagulopathy Non-coagulopathy P value
  (n = 82) (n = 37) (n = 45)  
Age (y) 45.3 ± 8.2 47.2 ± 7.1 41.5 ± 5.9 0.419
Male, n (%) 54 (65.9%) 26 (70.3%) 28 (62.2%) 0.490
Blunt trauma 79 (96.3%) 35 (94.6%) 44 (97.8%) 0.550
Type of trauma     
   Cerebral 18 8 10  
   Extremities 2 0 2  
   Abdominal 6 1 5  
   Thoracic 10 3 7  
   Multi trauma 43 24 19  
   Other 3 1 2  
ISS 27.6 ± 2.2 33.8 ± 3.5 23.3 ± 1.8 0.003
30-day mortality, n (%) 17 (20.7%) 13 (35.1%) 4 (8.9%) 0.004
Laboratory analyses on admission     
   sPsel (NR: 20–44 ng/mL) 54.8 ± 22.6 49.4 ± 26.0 59.5 ± 18.2 0.044
   VWF (NR: 66–176%) 224.1 (198.3-245.1) 205.8 (135.5-231.1) 244.2 (199.2-247.2) 0.014
   PTR (NR: 0.88-1.12) 1.18 (1.07-1.56) 1.68 (1.41-1.74) 1.08 (1.05-1.13) <0.001
   Protein C (NR: 70–130%) 76.7 ± 38.8 48.0 ± 19.1 101.5 ± 34.2 <0.001
   Factor VII (NR: 55–170%) 74.4 ± 37.0 46.0 ± 24.2 98.9 ± 27.5 <0.001
   Hemoglobin (NR: 110-160 g/L) 101.1 ± 29.9 90.3 ± 29.4 109.8 ± 27.6 0.022
   Glucose 8.39 ± 2.78 8.86 ± 3.15 8.09 ± 2.38 0.411
   (NR: 4.11-6.05 mmol/L)     
Transfusions in units for the first day     
   PLTC 1.5 (1.0-2.0) 1.5 (1.0-2.0) 0  
(n = 5) (n = 5)
   FFP 3.5 (2.5-7.0) 4.0 (3.0-7.5) 2 and 4 units 0.230
(n = 9) (n = 7) (n = 2)
   PRBC 2.5 (1.5-4.0) 2 and 2 units 2.5 (1–4.5) 0.315
  (n = 13) (n = 2) (n = 11)  
  1. Frequencies are given as count with percentage and were compared by the chi-square test. Transfusions (units) and admission VWF and PTR levels are given as medians (interquartile range) and were compared by the Mann–Whitney U test. Levels of other parameters, age, and ISS are given as means ± standard deviations and were compared by Student’s t test. ISS Injury Severity Score, NR normal range, PLTC platelet concentrates, FFP fresh frozen plasma, PRBC packed red blood cells.